1271949-71-3

Upstream product

• 1271949-59-7 (R)-2-methyl-propane-2-sulfinic acid [1-(2-fluoro-5-nitro-phenyl)-prop-(E)-ylidene]-amide 
• 461037-07-0 1-(2-fluoro-5-nitrophenyl)propan-1-one 
• 446-22-0 1-(2-fluorophenyl)propan-1-one 
• 1271949-69-9 2-((S)-3-chloro-1-ethyl-1-isothiocyanato-propyl)-1-fluoro-4-nitro-benzene 
• 1271949-67-7 (S)-3-(2-fluoro-5-nitro-phenyl)-3-isothiocyanato-pentan-1-ol 
• 1271949-65-5 (S)-3-amino-3-(2-fluoro-5-nitro-phenyl)-pentan-1-ol 
• 1271949-63-3 (S)-3-amino-3-(2-fluoro-5-nitrophenyl)pentanoic acid 

Downstream Products

• 1271949-73-5 [(S)-4-ethyl-4-(2-fluoro-5-nitro-phenyl)-5,6-dihydro-4H-[1,3]thiazin-2-yl]-carbamic acid tert-butyl ester 
• 1271949-75-7 [(S)-4-(5-amino-2-fluoro-phenyl)-4-ethyl-5,6-dihydro-4H-[1,3]thiazin-2-yl]-carbamic acid tert-butyl ester 
• 1271948-79-8 5-chloro-pyridine-2-carboxylic acid [3-((S)-2-amino-4-ethyl-5,6-dihydro-4H-[1,3]thiazin-4-yl)-4-fluoro-phenyl]-amide formate 

Relevant academic research and scientific papers

USE OF AMINODIHYDROTHIAZINES FOR THE TREATMENT OR PREVENTION OF DIABETES

This invention relates to compounds of formula I, wherein R1 to R3 are as defined herein, as well as pharmaceutically acceptable salts thereof, pharmaceutical compositions containing such compounds and methods for using such compound

2 -AMINODIHYDRO [1, 3] THIAZINES AS BACE 2 INHIBITORS FOR THE TREATMENT OF DIABETES

This invention relates to the use of aminodihydrothiazines of the formula wherein R1 to R3 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof, and pharmaceutical compositions con