461037-07-0

Basic information

• Product Name: 1-(2-fluoro-5-nitrophenyl)propan-1-one
• Synonyms: 1-(2-fluoro-5-nitrophenyl)propan-1-one
• CAS NO: 461037-07-0
• Molecular Weight: 197.166
• Mol File: 461037-07-0.mol

Chemical Properties

• CAS DataBase Reference: 1-(2-fluoro-5-nitrophenyl)propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-fluoro-5-nitrophenyl)propan-1-one(461037-07-0)
• EPA Substance Registry System: 1-(2-fluoro-5-nitrophenyl)propan-1-one(461037-07-0)

Safety Data

• Hazardous Substances Data: 461037-07-0(Hazardous Substances Data)

Upstream product

• 446-22-0 1-(2-fluorophenyl)propan-1-one 

Downstream Products

• 1271948-79-8 5-chloro-pyridine-2-carboxylic acid [3-((S)-2-amino-4-ethyl-5,6-dihydro-4H-[1,3]thiazin-4-yl)-4-fluoro-phenyl]-amide formate 
• 1271949-75-7 [(S)-4-(5-amino-2-fluoro-phenyl)-4-ethyl-5,6-dihydro-4H-[1,3]thiazin-2-yl]-carbamic acid tert-butyl ester 
• 1271949-73-5 [(S)-4-ethyl-4-(2-fluoro-5-nitro-phenyl)-5,6-dihydro-4H-[1,3]thiazin-2-yl]-carbamic acid tert-butyl ester 
• 1271949-71-3 (S)-4-ethyl-4-(2-fluoro-5-nitrophenyl)-5,6-dihydro-4H-[1,3]thiazin-2-ylamine 
• 1271949-69-9 2-((S)-3-chloro-1-ethyl-1-isothiocyanato-propyl)-1-fluoro-4-nitro-benzene 
• 1271949-67-7 (S)-3-(2-fluoro-5-nitro-phenyl)-3-isothiocyanato-pentan-1-ol 
• 1271949-65-5 (S)-3-amino-3-(2-fluoro-5-nitro-phenyl)-pentan-1-ol 
• 1271949-63-3 (S)-3-amino-3-(2-fluoro-5-nitrophenyl)pentanoic acid 
• 1271949-59-7 (R)-2-methyl-propane-2-sulfinic acid [1-(2-fluoro-5-nitro-phenyl)-prop-(E)-ylidene]-amide 

Relevant articles and documents

1,4-OXAZEPINES AS BACE1 AND/OR BACE2 INHIBITORS

This invention relates to compounds of the formula wherein and R1 to R3 are as described herein, or to pharmaceutically acceptable salts thereof. These compounds are BACE1 and/or BACE2 inhibitors and can be used as pharmaceuticals fo

FGFR2 MODULATORS

A compound of Formula (I), or a pharmaceutically acceptable salt thereof, wherein:R3a, R2, R3b, R4b, L1, G and J are as defined in the specification, pharmaceutical compositionsthereof, and methods of use thereof.

1,4-OXAZEPINES AS BACE1 AND/OR BACE2 INHIBITORS

The present invention relates to 1,4-Oxazepines of formula I having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the pres

1,4-OXAZEPINES AS BACE1 AND/OR BACE2 INHIBITORS

The present invention relates to 1,4-Oxazepines of formula I having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the pres

1,4-OXAZEPINES AS BACE1 AND/OR BACE2 INHIBITORS

This invention relates to compounds of the formula wherein and R1 to R3 are as described below, or to pharmaceutically acceptable salts thereof. These compounds are BACE1 and/or BACE2 inhibitors and can be used as medicaments for the therapeutic and/or pr

USE OF AMINODIHYDROTHIAZINES FOR THE TREATMENT OR PREVENTION OF DIABETES

This invention relates to compounds of formula I, wherein R1 to R3 are as defined herein, as well as pharmaceutically acceptable salts thereof, pharmaceutical compositions containing such compounds and methods for using such compound

2 -AMINODIHYDRO [1, 3] THIAZINES AS BACE 2 INHIBITORS FOR THE TREATMENT OF DIABETES

This invention relates to the use of aminodihydrothiazines of the formula wherein R1 to R3 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof, and pharmaceutical compositions con

AMINO OXAZINE DERIVATIVES

This invention relates to 5,6-dihydro-4H-[1,3]oxazin-2-ylamine compounds of the formula wherein R1 to R5 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are BACE2 inhibitors and can be used as medicaments for the treatment or prevention of diseases such as diabetes.

2-AMINO-5,5-DIFLUORO-5,6-DIHYDRO-4H-[1,3]OXAZIN-4-YL)-PHENYL]-AMIDES

The present invention relates to 2-Amino-5,5-difluoro-5,6-dihydro-4H-[1,3]oxazin-4-yl)-phenyl]-amides of formula I having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutical

AMINO OXAZINE DERIVATIVES

This invention relates to 5,6-dihydro-4H-[1,3]oxazin-2-ylamine compounds of the formula (I) wherein R1 to R5 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are BACE2 inhibitors and can be used as medicaments for the treatment or prevention of diseases such as diabetes.