127326-97-0Relevant academic research and scientific papers
Synthesis of 2-benzoylpyrrole derivatives via C-H functionalization adjacent to nitrogen of pyrrole
Guo, Zhiqiang,Wei, Xuehong,Hua, Yupeng,Chao, Jianbin,Liu, Diansheng
, p. 3919 - 3922 (2015)
A direct transition-metal-free synthesis of 2-benzoylpyrrole derivatives from free (N-H) pyrroles and benzaldehyde has been developed. The benzoylation reaction at the 2 or 5-position of pyrrole proceeded well under the alkali metalation system and with 2
Indolinone compounds as kinase inhibitors
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Page/Page column 79, (2010/11/30)
The invention relates to certain indolinone compounds, their method of synthesis, and a combinatorial library consisting of the indolinone compounds of the invention. The invention also relates to methods of modulating the function of protein kinases using indolinone compounds of the invention and methods of treating diseases by modulating the function of protein kinases and related signal transduction pathways.
