127356-38-1

Basic information

• Product Name: 4-PYRIDINAMINE, 2-METHOXY-5-NITRO-
• Synonyms: 4-PYRIDINAMINE, 2-METHOXY-5-NITRO-;4-Amino-2-methoxy-5-nitropyridine;2-Methoxy-5-nitropyridin-4-aMine;2-Methoxy-5-nitro-4-aMinopyridine;2-Methoxy-5-nitro-4-pyridinaMine;2-Methoxy-5-nitro-pyridin-4-ylamine
• CAS NO: 127356-38-1
• Molecular Formula: C₆H₇N₃O₃
• Molecular Weight: 169.139
• Mol File: 127356-38-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 138-141 °C
• Boiling Point: 383.2 °C at 760 mmHg
• Flash Point: 185.5 °C
• Appearance: /
• Density: 1.4 g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 3.19±0.42(Predicted)
• CAS DataBase Reference: 4-PYRIDINAMINE, 2-METHOXY-5-NITRO-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-PYRIDINAMINE, 2-METHOXY-5-NITRO-(127356-38-1)
• EPA Substance Registry System: 4-PYRIDINAMINE, 2-METHOXY-5-NITRO-(127356-38-1)

Safety Data

• Hazardous Substances Data: 127356-38-1(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of Medicinal Chemistry, 33, p. 2231, 1990 DOI: 10.1021/jm00170a030

Upstream product

• 67-56-1 methanol 
• 2604-39-9 4-amino-2-chloro-5-nitropyridine 
• 124-41-4 sodium methylate 
• 14432-12-3 4-Amino-2-chloropyridine 

Downstream Products

• 1096666-02-2 6-methoxy-1H-imidazo[4,5-c]pyridine 
• 127356-26-7 3,4-diamino-6-methoxypyridine 
• 127356-08-5 2-(4-Methanesulfinyl-2-methoxy-phenyl)-6-methoxy-1H-imidazo[4,5-c]pyridine 
• 127356-30-3 6-Methoxy-2-(2-methoxy-4-methylsulfanyl-phenyl)-1H-imidazo[4,5-c]pyridine 

Relevant articles and documents

Hepatitis C virus inhibitors

Hepatitis C virus inhibitors having the general formula (I) are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.

Thiophene-imidazopyridines

The invention relates to thiophene-imidazopyridine compounds according to formula (I), wherein the substituents and symbols are as defined in the description. The compounds are inhibitors of PIk1