127394-79-0Relevant academic research and scientific papers
New luminescent 2-methoxy-6-(4-methoxy-phenyl)-4-p-tolyl-nicotinonitrile: Synthesis, crystal structure, DFT and photophysical studies
Ahipa,Kamath, Pooja R.,Kumar, Vijith,Adhikari, Airody Vasudeva
, p. 230 - 236 (2014)
In the current communication, we report the synthesis, spectroscopic, crystal structure, DFT and photophysical studies of a new nicotinonitrile derivative, viz. 2-methoxy-6-(4-methoxy-phenyl)-4-p-tolyl-nicotinonitrile (2) as a potential blue light emitting material. The compound 2 was synthesized in good yield via a simple route. The acquired spectral and elemental analysis data were in consistent with the chemical structure of 2. The single crystal study further confirms its three dimensional structure, molecular shape, and nature of short contacts. Its DFT calculations reveal that compound 2 possesses a non-planar structure and its theoretical IR spectral data are found to be in accordance with experimental values. In addition, its UV-visible and fluorescence spectral measurements prove that the compound exhibits good absorption and fluorescence properties. Also, it shows positive solvatochromic effect when the solvent polarity was varied from non-polar to polar.
Synthesis of polysubstituted pyridines under combined microwave and ultrasound irradiation: K2CO3-promoted tandem addition/cyclization/hydrogen shift process
Feng, Huangdi,Li, Yuan,Van Der Eycken, Erik V.,Peng, Yanqing,Song, Gonghua
, p. 1160 - 1162 (2012/03/26)
A convenient and efficient K2CO3-promoted tandem reaction of chalcone, malononitrile, and methanol for the synthesis of highly functionalized pyridines has been developed. This multi-component reaction employing the weak nucleophilic agent methanol proceeded smoothly under combined microwave and ultrasound irradiation (CMUI). The reaction mechanism was proposed to consist of a Michael addition, a methoxylation of CN bond, a cyclization to a 1,4-dihydropyridine and an intermolecular hydrogen shift between 1,4-dihydropyridine and initial chalcone.
A Facile Synthesis of 6-Alkoxy-2,4-diaryl-5-cyanopyridine
Al-Arab, Mohammad M.
, p. 1665 - 1673 (2007/10/02)
A new synthesis of substituted pyridine is reported.The base catalyzed reaction of substituted chalcones with malononitrile using sodium ethoxide in ethanol at room temperature afforded 2,4-diaryl-5-cyano-6-ethoxypyridine.Similarly, 2,4-diaryl-5-cyano-6-methoxypyridine have been prepared in presence of sodium methoxide in methanol as a catalyst.
