127446-47-3 Usage
Medicinal Use
Treatment of rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis
Mechanism of Action
Janus kinase (JAK) inhibitor
Enzyme Inhibition
Blocks certain enzymes involved in the immune system and inflammation
Effect on Inflammatory Conditions
Reduces symptoms and progression of the diseases
Pharmaceutical Form
Tablet
Prescription
Typically prescribed by a healthcare professional
Chronic Inflammatory Disease Management
Used for managing chronic inflammatory diseases
Check Digit Verification of cas no
The CAS Registry Mumber 127446-47-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,4,4 and 6 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 127446-47:
(8*1)+(7*2)+(6*7)+(5*4)+(4*4)+(3*6)+(2*4)+(1*7)=133
133 % 10 = 3
So 127446-47-3 is a valid CAS Registry Number.
127446-47-3Relevant academic research and scientific papers
A General Approach to the Synthesis of 1,6-, 1,7-, and 1,8-Naphthyridines
Turner, James A.
, p. 4744 - 4750 (2007/10/02)
A new three-step procedure for pyridine annulation is described and illustrated with efficient syntheses of various 1,6-, 1,7-, and 1,8-naphthyridin-2-ones as well as 6-chloroquinolin-2-one.The regiospecific ortho metalation and subsequent formylation of
