127459-32-9Relevant academic research and scientific papers
Synthetic studies using unsaturated and active phosphonium salts. A convenient preparation of furano- and pyrano[2,3-c]pyridazines and substituted quinolines
Abdou, Wafaa M.,Ganoub, Neven A.,Fahmy, Amin F.,Shaddy, Abeer M.
, p. 56 - 64 (2005)
By applying vinyl- (3) and allyltriphenyl-phosphonium bromides (9) to 4-cyano-5,6-difur-2′yl-2H-pyridazin-3-one (1) the corresponding fused 5,8-oxazolo- 6, 12 (～37%) and pyrano- 8, 13, 14 (～20%) derivatives are isolated whereas with alkylphosphonium bromides 15a,b fused furans 17a,b (22%) and isopyrroles 18a,b (～45%) are obtained. On the other hand, the reaction of 2-[(benzylidene)amino]-benzonitrile (2) with 3 and 9 yielded benzoazepines 20 and 21 (～56%). With 15a,b, quinolines 23a,b (～46%) and quinazoline 25 (～24%) are obtained.
ADDITION AND LITHIATION REACTIONS OF N-(1-PHENYLALKYLIDENE)ANILINES WITH LITHIUM DIALKYLAMIDES
Strekowski, Lucjan,Patterson, Steven,Cegla, Marek T.,Wydra, Roman L.,Czarny, Agnieska,Harden, Donald B.
, p. 5197 - 5200 (2007/10/02)
Lithium diisopropylamide undergoes an addition reaction to the methyleneamino moiety of the title Schiff's bases substituted with a cyano group at the orto or para position of the aniline, but mediates tautomerization of the unsubstituted and metasubstitu
