127605-37-2 Usage
Molecular structure
1-tert-Butyl 4-methyl 2-(benzyloxycarbonylamino)succinate consists of a tert-butyl group, a methyl group, a benzyloxycarbonylamino group, and a succinate backbone.
Functional groups
The compound contains a tert-butyl group (t-Bu), a methyl group (CH3), and a benzyloxycarbonylamino group (C6H5CH2OCONH-).
Protecting group
The tert-butyl and benzyloxycarbonyl groups act as protecting groups for amino acids during chemical reactions.
Applications
The compound is commonly used in organic synthesis and drug development, and has potential applications in the pharmaceutical industry for the synthesis of new drug candidates.
Selective manipulation
The protecting groups allow for selective manipulation of molecules, enabling the synthesis of more complex molecules with greater precision.
Use in research and development
The compound may also be used in the chemical and biotechnology sectors for research and development of new products.
Check Digit Verification of cas no
The CAS Registry Mumber 127605-37-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,6,0 and 5 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 127605-37:
(8*1)+(7*2)+(6*7)+(5*6)+(4*0)+(3*5)+(2*3)+(1*7)=122
122 % 10 = 2
So 127605-37-2 is a valid CAS Registry Number.
127605-37-2Relevant academic research and scientific papers
Asymmetric Amino Acid Synthesis: Preparation of the β Anion derived from Aspartic Acid
Baldwin, Jack E.,Moloney, Mark G.,North, Michael
, p. 833 - 834 (2007/10/02)
(S)-1-t-Butyl 4-methyl N-benzyloxycarbonylaspartate (5a), and (S)-1-t-butyl 4-allyl N-benzyloxycarbonylaspartate (5b) have been synthesized from (S)-aspartic acid (2), and can be readily alkylated and hydroxyalkylated at the β-carbon for asymmetric amino acid synthesis.
Non-Proteinogenic Amino Acid Synthesis. The β-Anion Derived from Aspartic Acid, and its Application to α-Amino Acid Synthesis.
Baldwin, Jack E.,Moloney, Mark G.,North, Michael
, p. 6309 - 6318 (2007/10/02)
Treatment of α-t-butyl β-methyl N-Z-(S)-aspartate (2) with lithium amide bases generates the corresponding β-ester enolate, which can be alkylated with suitable electrophiles.The application of this strategy for synthesis of optically active amino acids h
