127605-48-5

Basic information

• Product Name: t-butyl 2-amino-3-carbomethoxy-4-phenyl-(2S)-butanoate
• CAS NO: 127605-48-5
• Molecular Weight: 293.363
• Mol File: 127605-48-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: t-butyl 2-amino-3-carbomethoxy-4-phenyl-(2S)-butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: t-butyl 2-amino-3-carbomethoxy-4-phenyl-(2S)-butanoate(127605-48-5)
• EPA Substance Registry System: t-butyl 2-amino-3-carbomethoxy-4-phenyl-(2S)-butanoate(127605-48-5)

Safety Data

• Hazardous Substances Data: 127605-48-5(Hazardous Substances Data)

Upstream product

• 123975-52-0 t-butyl 2-benzyloxycarbonylamino-3-carbomethoxy-4-phenyl-(2RS)-butanoate 
• 123975-52-0 t-butyl 2-benzyloxycarbonylamino-3-carbomethoxy-4-phenyl-(2S)-butanoate 
• 3160-47-2 N-(benzyloxycarbonyl)-L-aspartic acid 4-methyl ester 
• 100-39-0 benzyl bromide 
• 60079-12-1 β-Methyl α-tert-butyl (2S)-N-(benzyloxycarbonyl)aspartate 
• 47307-26-6 (S)-2-benzyloxycarbonylamino-succinic acid 1-tert-butyl ester 
• 4276-08-8 β-methyl N-benzyloxycarbonyl-DL-aspartate 
• 127605-37-2 α-t-butyl β-methyl N-Z-(RS)-aspartate 
• 620-05-3 iodomethylbenzene 
• 128576-87-4 (2S,3S)-4-benzyl 1-tert-butyl N-benzyl-N-(9-phenylfluoren-9-yl)-3-benzylaspartate 
• 128576-67-0 (2S,3S)-1-tert-butyl N-benzyl-N-(9-phenylfluoren-9-yl)-3-benzylaspartate 
• 128599-28-0 (2S)-4-benzyl 1-tert-butyl N-benzyl-N-(9-phenylfluoren-9-yl)aspartate 
• 128576-61-4 1-(tert-butyl) 4-methyl N-benzyl-N-(9-phenyl-9H-fluoren-9-yl)-L-aspartate 
• 128576-65-8 (2S)-4-benzyl 1-tert-butyl N-benzylaspartate 

Downstream Products

• 128576-64-7 (2S,3S) and (2S,3R)-1-tert-butyl N-(tert-butoxycarbonyl)-3-benzylaspartate 
• 123975-65-5 t-butyl N-(2-methoxy-2-phenyl-3,3,3-trifluoro-(R)-propionoyl)-2-amino-3-carbomethoxy-4-phenyl-(2S)-butanoate 
• 123975-65-5 t-butyl N-(2-methoxy-2-phenyl-3,3,3-trifluoro-(R)-propionoyl)-2-amino-3-carbomethoxy-4-phenyl-(2RS)-butanoate 
• 133637-87-3 (4S,5R)-1,5-Dibenzyl-2-[(E)-cyanoimino]-6-oxo-hexahydro-pyrimidine-4-carboxylic acid tert-butyl ester 
• 133637-93-1 (4S,5S)-1,5-Dibenzyl-2-[(E)-cyanoimino]-6-oxo-hexahydro-pyrimidine-4-carboxylic acid tert-butyl ester 
• 133637-88-4 2-{1-Benzyl-2-[(E)-cyanoimino]-5-oxo-imidazolidin-4-yl}-3-phenyl-propionic acid methyl ester 
• 133637-86-2 C₂₄H₂₇N₃O₅ 
• 133637-86-2 C₂₄H₂₇N₃O₅ 
• 128576-63-6 (2S,3S)-1-tert-butyl 4-methyl N-(tert-butoxycarbonyl)-3-benzylaspartate 

Relevant articles and documents

Regioselective and enantiospecific synthesis of 6-substituted and 5,6-disubstituted hexahydropyrimidines

The preference for 5- over 6-membered rings in the intramolecular cyclisation of amines with diesters can be partially overcome with mixed methyl (or benzyl), tert-butyl diesters, and this effect is enhanced where there is a β-substituent. The hexahydropy

Asymmetric Amino Acid Synthesis: Preparation of the β Anion derived from Aspartic Acid

(S)-1-t-Butyl 4-methyl N-benzyloxycarbonylaspartate (5a), and (S)-1-t-butyl 4-allyl N-benzyloxycarbonylaspartate (5b) have been synthesized from (S)-aspartic acid (2), and can be readily alkylated and hydroxyalkylated at the β-carbon for asymmetric amino acid synthesis.