123975-64-4

Upstream product

• 39637-99-5 (S)-(+)-2-methoxy-2-trifluoromethyl-2-phenylacetyl chloride 
• 127605-38-3 t-butyl 2-amino-3-carbomethoxy-4-hydroxy-4-phenyl-(2RS)-butanoate 
• 20445-33-4 (R)-methoxytrifluoromethylphenylacetyl chloride 
• 127605-37-2 α-t-butyl β-methyl N-Z-(RS)-aspartate 
• 123975-51-9 t-butyl 2-benzyloxycarbonylamino-3-carbomethoxy-4-hydroxy-4-phenyl-(2RS)-butanoate 
• 4276-08-8 β-methyl N-benzyloxycarbonyl-DL-aspartate 
• 100-52-7 benzaldehyde 
• 127605-38-3 t-butyl 2-amino-3-carbomethoxy-4-hydroxy-4-phenyl-(2S)-butanoate 
• 47307-26-6 (S)-2-benzyloxycarbonylamino-succinic acid 1-tert-butyl ester 
• 60079-12-1 β-Methyl α-tert-butyl (2S)-N-(benzyloxycarbonyl)aspartate 
• 123975-50-8 (S)-N-benzyloxycarbonylaspartic acid α-tert-butyl β-allyl ester 
• 123975-51-9 t-butyl 2-benzyloxycarbonylamino-3-carbomethoxy-4-hydroxy-4-phenyl-(2S)-butanoate 
• 3160-47-2 N-(benzyloxycarbonyl)-L-aspartic acid 4-methyl ester 

Relevant academic research and scientific papers

Asymmetric Amino Acid Synthesis: Preparation of the β Anion derived from Aspartic Acid

(S)-1-t-Butyl 4-methyl N-benzyloxycarbonylaspartate (5a), and (S)-1-t-butyl 4-allyl N-benzyloxycarbonylaspartate (5b) have been synthesized from (S)-aspartic acid (2), and can be readily alkylated and hydroxyalkylated at the β-carbon for asymmetric amino acid synthesis.

Non-Proteinogenic Amino Acid Synthesis: Synthesis of β,γ-Unsaturated α-Amino Acids from Aspartic Acid

A general, stereospecific, synthesis of β,γ-unsaturated α-amino acids using the β-anion derived from aspartic acid is described.Keywords: aspartic acid; unsaturated acids