4276-08-8

Upstream product

• 1835-52-5 L-Aspartic acid beta-methyl ester hydrochloride 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 106063-08-5 (-)-N-Cbz-β-methyl-D-aspartyl-α-PNB-β-methyl-L-aspartate 
• 127605-37-2 α-t-butyl β-methyl N-Z-(RS)-aspartate 
• 350238-06-1 3-benzyloxycarbonylamino-N-(5-chloro-2-phenylcarbamoylacetyl-phenyl)-succinamic acid methyl ester 
• 116116-14-4 Z-Asp(OCH₃)-PheOCH₃ 
• 123975-64-4 t-butyl N(2-methoxy-2-phenyl-3,3,3-trifluoro-(R)-propionoyl)-2-amino-3-carbomethoxy-4-hydroxy-4-phenyl-(2RS)-butanoate 
• 123975-65-5 t-butyl N-(2-methoxy-2-phenyl-3,3,3-trifluoro-(R)-propionoyl)-2-amino-3-carbomethoxy-4-phenyl-(2RS)-butanoate 
• 123975-51-9 t-butyl 2-benzyloxycarbonylamino-3-carbomethoxy-4-hydroxy-4-phenyl-(2RS)-butanoate 
• 123975-52-0 t-butyl 2-benzyloxycarbonylamino-3-carbomethoxy-4-phenyl-(2RS)-butanoate 
• 127605-38-3 t-butyl 2-amino-3-carbomethoxy-4-hydroxy-4-phenyl-(2RS)-butanoate 
• 127605-48-5 t-butyl 2-amino-3-carbomethoxy-4-phenyl-(2RS)-butanoate 
• 420803-14-1 methyl 7-chloro-5-(2-chlorophenyl)-1-isobutyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepine-3-acetate 
• 420803-13-0 methyl 7-chloro-5-(2-chlorophenyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepine-3-acetate 

Relevant academic research and scientific papers

Asymmetric Amino Acid Synthesis: Preparation of the β Anion derived from Aspartic Acid

(S)-1-t-Butyl 4-methyl N-benzyloxycarbonylaspartate (5a), and (S)-1-t-butyl 4-allyl N-benzyloxycarbonylaspartate (5b) have been synthesized from (S)-aspartic acid (2), and can be readily alkylated and hydroxyalkylated at the β-carbon for asymmetric amino acid synthesis.