127654-98-2

Upstream product

• 100-39-0 benzyl bromide 
• 127654-97-1 cis-2,5-bis(ethoxycarbonylmethyl)pyrrolidine 
• 127654-95-9 (1-benzyl-2,5-bis-ethoxycarbonylmethylene)pyrrolidine 
• 67501-92-2 N-(t-butyldimethylsilyl)-4-(2-hydroxyethyl)-azetidin-2-one 
• 109533-20-2 4-(2-Bromethyl)-2-azetidinon 
• 100118-09-0 diethyl hexa-1,5-diyne-1,6-dicarboxylate 
• 127654-96-0 (1-benzyl-2,5-bis-ethoxycarbonylmethylene)pyrrolidine 
• 2142-06-5 1-(phenylmethyl)-2,5-pyrrolidinedione 

Downstream Products

• 127655-00-9 1-benzyl-2,5-cis-pyrrolidinyldiethanol 
• 127655-04-3 12-benzyl-4,6-dioxa-12-azabicyclo<7.2.1>dodecan-5-one 
• 127655-02-1 12-benzyl-4,6-dioxa-12-azabicyclo<7.2.1>dodecane-5-thione 
• 127655-07-6 2,5-cis-1-benzyl-2-(2-chloroethyl)-7-oxa-1-azaspiro<4.4.>nonan-6-one 
• 127655-05-4 2,5-cis-1-benzyl-2-(2-hydroxyethyl)-7-oxa-1-azaspiro<4.4>nonan-6-one 
• 127655-06-5 2,5-cis-1-benzyl-2-(2-tert-butyldimethylsilyloxyethyl)-7-oxa-1-azaspiro<4.4.>nonan-6-one 
• 127655-08-7 2,5-cis-1-benzyl-2-(2-p-bromobenzoyloxyethyl)-7-oxa-1-azaspiro<4.4.>nonan-6-one 

Relevant academic research and scientific papers

Radical cyclization of β-aminoacrylates: Synthesis of bicyclic pyrrolidine derivatives

Radical cyclization of the β-aminoacrylate derived from 4-(2- bromoethyl)azetidin-2-one led to the stereoselective formation of a bicyclic β-lactam product, which may serve as a precursor for cis-2,5-disubstituted pyrrolidines. (C) 2000 Elsevier Science L

Novel Transformation of Azabicyclothionocarbonate to Azaspirolactone

Treatment of azabicyclothionocarbonate (6a) with a catalytic amount of α,α'-azobisisobutyronitrile in refluxing benzene leads to the formation of a new azaspirolactone (8), whose structure was unambiguously established by an X-ray analysis.A mechanism is