1277175-21-9

Basic information

• Product Name: N-(benzofuran-2-yl)-4-methoxybenzamide
• Synonyms: N-(benzofuran-2-yl)-4-methoxybenzamide
• CAS NO: 1277175-21-9
• Molecular Weight: 267.284
• Mol File: 1277175-21-9.mol

Chemical Properties

• CAS DataBase Reference: N-(benzofuran-2-yl)-4-methoxybenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(benzofuran-2-yl)-4-methoxybenzamide(1277175-21-9)
• EPA Substance Registry System: N-(benzofuran-2-yl)-4-methoxybenzamide(1277175-21-9)

Safety Data

• Hazardous Substances Data: 1277175-21-9(Hazardous Substances Data)

Upstream product

• 100-07-2 4-methoxy-benzoyl chloride 
• 271-89-6 1-benzofurane 
• 3532-17-0 4-methoxybenzoyl azide 
• 1277175-87-7 N-(3-bromobenzofuran-2-yl)-4-methoxybenzamide 
• 98-80-6 phenylboronic acid 
• 5720-07-0 4-methoxyphenylboronic acid 
• 1277175-91-3 benzyl bromo(3-bromobenzofuran-2-yl)carbamate 
• 1277175-25-3 benzyl 3-bromobenzofuran-2-ylcarbamate 
• 1277175-00-4 benzyl benzofuran-2-yl(benzoyl)carbamate 
• 496-41-3 Benzofuran-2-carboxylic acid 
• 916605-99-7 benzyl benzofuran-2-ylcarbamate 

Downstream Products

• 1277175-87-7 N-(3-bromobenzofuran-2-yl)-4-methoxybenzamide 
• 1277175-79-7 4-methoxy-N-(3-phenylbenzofuran-2-yl)benzamide 
• 1277175-84-4 4-methoxy-N-(3-(4-methoxyphenyl)benzofuran-2-yl)benzamide 

Relevant articles and documents

Visible light C-H amidation of heteroarenes with benzoyl azides

Benzoyl azides were used for the direct and atom economic C-H amidation of electron rich heteroarenes in the presence of phosphoric acid, a photocatalyst and visible light. Hetero-aromatic amides are obtained in good yields at very mild reaction conditions with dinitrogen as the only by-product. The reaction allows the use of aryl-, heteroaryl- or alkenyl acyl azides and has a wide scope for heteroarenes, including pyrroles, indole, furan, benzofuran and thiophene giving good regio-selectivities and yields.

Synthesis of 3-aryl-2-arylamidobenzofurans based on the curtius rearrangement

The synthesis of novel 3-aryl-2-arylamidobenzofurans has been accomplished via a Curtius rearrangement strategy in four steps from benzofuran-2-carboxylic acids. The requisite Suzuki-Miyaura cross-coupling, with benzyl 3-bromobenzofuran-2-ylcarbamate or 2