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N-(piperidin-2-ylmethyl)benzamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 127722-73-0 Structure
  • Basic information

    1. Product Name: N-(piperidin-2-ylmethyl)benzamide
    2. Synonyms: N-(piperidin-2-ylmethyl)benzamide;N-(2-PIPERIDINYLMETHYL)BENZAMIDE
    3. CAS NO:127722-73-0
    4. Molecular Formula: C13H18N2O
    5. Molecular Weight: 218.298
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 127722-73-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N-(piperidin-2-ylmethyl)benzamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: N-(piperidin-2-ylmethyl)benzamide(127722-73-0)
    11. EPA Substance Registry System: N-(piperidin-2-ylmethyl)benzamide(127722-73-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 127722-73-0(Hazardous Substances Data)

127722-73-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 127722-73-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,7,2 and 2 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 127722-73:
(8*1)+(7*2)+(6*7)+(5*7)+(4*2)+(3*2)+(2*7)+(1*3)=130
130 % 10 = 0
So 127722-73-0 is a valid CAS Registry Number.

127722-73-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name N-[((2-piperidinyl)methyl)]benzamide

1.2 Other means of identification

Product number -
Other names N-(PIPERIDIN-2-YLMETHYL)BENZAMIDE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:127722-73-0 SDS

127722-73-0Downstream Products

127722-73-0Relevant articles and documents

On DABAL-Me3 promoted formation of amides

Dubois, Nathalie,Glynn, Daniel,McInally, Thomas,Rhodes, Barrie,Woodward, Simon,Irvine, Derek J.,Dodds, Chris

supporting information, p. 9890 - 9897 (2013/10/22)

The range and utility of DABAL-Me3 couplings of methyl esters and free carboxylic acids with primary and secondary amines under a variety of conditions (reflux, sealed tube, microwave) has been compared for a significant range of coupling partners of relevance to the preparation of amides of interest in pharmaceutical chemistry. Commercial microwave reactors promote the fastest couplings and allow the use of significantly sterically hindered amines (primary and secondary) and carboxylic acids derivatives. The influence of microwave energy on the reaction system was shown to be typically related to thermal effects (over-pressuring and superheating).

Determination of enantiomeric purity of 2-piperidinemethanamine by HPLC combined with pre-column derivation

Zhang, Yi-Wen,Luo, Ji,Zeng, Hao,Yao, Shun,Chen, Hao,Song, Hang

, p. 1353 - 1356 (2013/05/21)

A new HPLC method has been developed and validated for determination of enantiomeric purity of 2-piperidinemethanamine within a short run time of less than 10 min. The method was based on pre-column derivation of 2-piperidinemethanamine with 3,5-dinitrobenzoic acid and complete separation of enantiomers has been achieved on a CHI-DMB analytical column (250 mm × 4.6 mm) using n-hexane: ethanol (85:15 v/v) as mobile phase at a flow rate of 1.0 mL min-1 under UV photodiode-array detector detection. Then the effects of mobile phase and temperature on enantioselectivity were further evaluated. The method was validated with respect to precision, accuracy, linearity, limit of detection (LOD), limit of quantification (LOQ) and robustness. The recoveries were between 99.1 and 102.3 % with percentage relative standard deviation less than 1.17 %. The LOD and LOQ for first enantiomer were 13.7 and 46.3 μg mL-1 and for second enantiomer were 15.2 and 51.4 μg mL-1, respectively. This method is expected to be accurate, stable, rapid and sensitive for determination of the enantiomeric purity of 2-piperidinemethanamine in bulk samples. Copyright

Non-acidic anti-inflammatory compounds: activity of N-(4,6-dimethyl-2-pyridinyl) benzamides and derivatives

Robert-Piessard, Sylvie,Le Baut, Guillaume,Courant, Jacqueline,Brion, Jean-Daniel,Sparfel, Louis,et al.

, p. 9 - 19 (2007/10/02)

The inhibition of the carragenin-induced rat-paw edema by previously synthesized N-(4,6-dimethyl)-2-pyridinyl) benzamides was evaluated.Amoung the 29 tested compounds, secondary benzamides 1, 12 and tertiary benzamide 60 exhibited a significant anti-inflammatory activity.It prompted us to envision a pharmacomodulation in this series by structural modifications on the homocycle, the amide function and the heterocycle.Although benzamide 38, acetamide 50 and benzylamine 56 elicited marked inhibitory activity, none was more active than N-(4,6-dimethyl-2-pyridinyl) benzamide 1. The mechanism of the anti-inflammatory action of 1 was investigated.The results showed that this molecule reduced eicosanoid biosynthesis but was unable to reduce cyclooxygenase or lipoxygenase activities.Although it did not directly block phospholipase activity, however, an inhibitory process at this level is likely.

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