127792-77-2

Usage

Usage

Synthesis of pharmaceuticals and agrochemicals

Chemical Structure

Pyridine derivative with a nitro group and a benzyloxy group attached to the sixth carbon atom

Functional Group

Acetonitrile

Versatility

Acts as a versatile building block for the synthesis of various organic compounds

Applications

Development of new drugs and pesticides
Synthetic organic chemistry

Safety

Requires careful handling and adherence to proper safety protocols in laboratory settings

Upstream product

• 75926-54-4 2-(benzyloxy)-5-nitropyridine 
• 3598-13-8 (4-chlorophenoxy)acetonitrile 

Downstream Products

• 17288-41-4 5-(benzyloxy)pyrrolo<3,2-b>pyridine 
• 127792-75-0 1,4-dihydro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-5H-pyrrol[3,2-b]pyridin-5-one 
• 17322-91-7 pyrrolo<3,2-b>pyrid-5-one 

Relevant academic research and scientific papers

3-(1,2,5,6-Tetrahydropyrid-4-yl)pyrrolo[3,2-b]pyrid-5-one: a potent and selective serotonin (5-HT(1B)) agonist and rotationally restricted phenolic analogue of 5-methoxy-3-(1,2,5,6-tetrahydropyrid-4-yl)indole

The synthesis and in vitro and in vivo characteristics of 3-(1,2,5,6-tetrahydropyrid-4-yl)pyrrolo[3,2-b]pyrid-5-one (1, CP-93,129) are described. This rotationally restricted phenolic analogue of RU-24,969 is a potent (15 nM) and selective (200x vs the 5-

THE SYNTHESIS OF ROTATIONALY RESTRICTED PHENOLIC ANALOG OF 5-METHOXY-3-(1,2,5,6-TETRAHYDROPYRID-4-YL)INDOLE (RU-24,969)

Pyrrolopyrid-5-one represents a rotationally restricted phenolic analog of 5-hydroxyindole.The synthesis of the rotationally restricted phenolic analog of the serotonin agonist, 5-methoxy-3-(1,2,5,6-tetrahydropyrid-4-yl)indole (RU-24,969), is prese