17288-41-4

Usage

Uses

Used in Pharmaceutical Development:
5-(benzyloxy)-1H-pyrrolo[3,2-b]pyridine is used as a potential pharmaceutical agent for the development of new drugs. Its unique structure and properties make it a promising candidate for various therapeutic applications, including the treatment of diseases and disorders.
Used in Organic Synthesis:
In the field of organic synthesis, 5-(benzyloxy)-1H-pyrrolo[3,2-b]pyridine serves as a valuable building block for the construction of more complex molecules. Its versatile chemical properties allow it to be incorporated into a wide range of organic compounds, contributing to the advancement of chemical research and the development of novel materials.
Used in Chemical Research:
5-(benzyloxy)-1H-pyrrolo[3,2-b]pyridine is utilized in chemical research to explore its properties and potential applications. Its unique structure provides a foundation for studying various chemical reactions and interactions, contributing to a deeper understanding of the underlying principles of chemistry and the discovery of new chemical phenomena.
Used in Medicinal Chemistry:
In the realm of medicinal chemistry, 5-(benzyloxy)-1H-pyrrolo[3,2-b]pyridine is employed as a key component in the design and synthesis of new pharmaceutical compounds. Its potential to modulate biological targets and exhibit therapeutic effects makes it a valuable tool for the development of innovative treatments and therapies.
Used in Drug Discovery:
5-(benzyloxy)-1H-pyrrolo[3,2-b]pyridine plays a crucial role in drug discovery, where it is used to identify and optimize potential drug candidates. Its unique structure and properties enable researchers to explore its interactions with biological targets, facilitating the development of new drugs with improved efficacy and selectivity.

InChI:InChI=1/C14H12N2O/c1-2-4-11(5-3-1)10-17-14-7-6-12-13(16-14)8-9-15-12/h1-9,15H,10H2

Upstream product

• 75926-54-4 2-(benzyloxy)-5-nitropyridine 
• 127792-77-2 2-<6-(benzyloxy)-3-nitro-2-pyridyl>acetonitrile 

Downstream Products

• 127792-75-0 1,4-dihydro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-5H-pyrrol[3,2-b]pyridin-5-one 
• 17322-91-7 pyrrolo<3,2-b>pyrid-5-one 

Relevant academic research and scientific papers

Pharmaceutically active 3-(1,2,5,6-tetrahydropyridyl)-pyrrolopyridines

Compounds of the formula STR1 wherein one of A, B, D and E is N and the remaining three atoms are C; R1 and R2 are independently selected from hydrogen and C1 to C6 alkyl; and R3, R4, R5 and R6 are independently selected from hydrogen, halogen, hydroxy, C1 -C6 alkyl, C1 -C8 alkoxy, phenyl-C1 -C6 alkoxy, phenoxy --NR7 R8 wherein R7 and R8 are independently selected from hydrogen, C1 -C8 alkyl, C1 -C6 alkanoyl and COOR9 wherein R9 is hydrogen or C1 -C6 alkyl, cyano, COOR10 wherein R10 is hydrogen or C1 -C6 alkyl, and CONR11 R12 where R10 and R11 are independently selected from hydrogen and C1 -C6 alkyl, and the pharmaceutically acceptable salts thereof. The compounds are useful psychotherapeutics and may be used in treating obesity, depression and disorders wherein aggression is a symptom.

THE SYNTHESIS OF ROTATIONALY RESTRICTED PHENOLIC ANALOG OF 5-METHOXY-3-(1,2,5,6-TETRAHYDROPYRID-4-YL)INDOLE (RU-24,969)

Pyrrolopyrid-5-one represents a rotationally restricted phenolic analog of 5-hydroxyindole.The synthesis of the rotationally restricted phenolic analog of the serotonin agonist, 5-methoxy-3-(1,2,5,6-tetrahydropyrid-4-yl)indole (RU-24,969), is prese

3-(1,2,5,6-Tetrahydropyrid-4-yl)pyrrolo[3,2-b]pyrid-5-one: a potent and selective serotonin (5-HT(1B)) agonist and rotationally restricted phenolic analogue of 5-methoxy-3-(1,2,5,6-tetrahydropyrid-4-yl)indole

The synthesis and in vitro and in vivo characteristics of 3-(1,2,5,6-tetrahydropyrid-4-yl)pyrrolo[3,2-b]pyrid-5-one (1, CP-93,129) are described. This rotationally restricted phenolic analogue of RU-24,969 is a potent (15 nM) and selective (200x vs the 5-