75926-54-4

Usage

Uses

Used in Pharmaceutical Synthesis:
2-(Benzyloxy)-5-nitropyridine is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its reactivity allows for the formation of diverse chemical structures, contributing to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Synthesis:
In the agrochemical industry, 2-(Benzyloxy)-5-nitropyridine serves as a crucial building block for the creation of novel agrochemicals. Its ability to undergo various chemical reactions enables the synthesis of compounds with potential applications in crop protection and pest control.
Used in Materials Science:
2-(Benzyloxy)-5-nitropyridine has potential applications in the field of materials science. Its unique chemical structure can be utilized to develop new materials with specific properties, such as improved stability, reactivity, or selectivity.
Used in Organic Synthesis:
As a versatile organic compound, 2-(Benzyloxy)-5-nitropyridine is employed in organic synthesis for the preparation of various organic molecules. Its reactivity and ability to participate in different types of chemical reactions make it a valuable component in the synthesis of complex organic structures.

InChI:InChI=1/C12H10N2O3/c15-14(16)11-6-7-12(13-8-11)17-9-10-4-2-1-3-5-10/h1-8H,9H2

Upstream product

• 620-05-3 iodomethylbenzene 
• 4548-45-2 2-chloro-5-nitropyridine 
• 100-51-6 benzyl alcohol 

Downstream Products

• 75926-65-7 3-amino-6-(benzyloxy)pyridine 
• 127792-77-2 2-<6-(benzyloxy)-3-nitro-2-pyridyl>acetonitrile 
• 17322-91-7 pyrrolo<3,2-b>pyrid-5-one 
• 17288-41-4 5-(benzyloxy)pyrrolo<3,2-b>pyridine 
• 127792-75-0 1,4-dihydro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-5H-pyrrol[3,2-b]pyridin-5-one 
• 1343488-82-3 N-(6-benzyloxy-pyridin-3-yl)-benzenesulfonamide 
• 1343488-87-8 N-(6-hydroxy-pyridin-3-yl)-benzenesulfonamide 
• 59892-44-3 1-benzyl-5-nitropyridin-2(1H)-one 

Relevant academic research and scientific papers

A nucleobase analogue that pairs strongly with adenine

Shaping up for an A: Adenine is the only canonical nucleobase that does not offer a third hydrogen-bonding functionality at its Watson-Crick face, making it difficult to bind with high affinity. A 6-ethynyl-2-pyridone binds more tightly and with greater sequence fidelity than thymine. VdW=van der Waals interactions. Copyright

Synthesis of 5-substituted 2,3-dihydrobenzofurans in a one-pot oxidation/cyclization reaction

Variously substituted 2,3-dihydrobenzofurans have been synthesized according to a sequential one-pot oxidation/cyclization procedure between para-aminophenol derivatives and an azadiene.

PHTHALANILATE COMPOUNDS AND METHODS OF USE

The invention provides antimicrobial compounds and compositions, and methods of using them. The compounds and compositions include, for example, a compound of any one of Formulas I-X. The invention further provides methods of preparing the compounds, and useful intermediates for their preparation. The compounds can possess highly specific and selective activity, such as antibacterial activity and/or enzymatic inhibitory activity. Accordingly, the compounds and compositions can be used to treat bacterial infections, or to inhibit or kill bacteria, either in vitro or in vivo.

NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE

The present invention relates to piperazine derivatives that act as inhibitors of stearoyl-CoA desaturase. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds.

CHEMICAL COMPOUNDS

This invention relates to non-steroidal compounds that are modulators of androgen, glucocorticoid, mineralocorticoid, and progesterone receptors, and also to the methods for the making and use of such compounds.

Substitution reactions of 5-nitropyridine-2-sulfonic acid. A new pathway to 2,5-disubstituted pyridines

We have investigated reactions of 5-nitropyridine-2-sulfonic acid and its potassium salt in which substitution of the sulfonate group by oxygen, nitrogen and halogen nucleophiles has been attempted. By this approach, 2-methoxy-(95% yield), 2-ethoxy- (97%), 2-isopropoxy- (65%), 2-amino- (92%), 2- butylamino- (76%), 2-diethylamino- (62%), 2-ethylamino- (32%), 2-benzylamino- (77%), 2-(R-1-phenylethylamino)- (71%) and 2-chloro-5-nitropyridine (87%) have been obtained. No reactions were observed with phenols or anilines. With t-BuOH, 2-hydroxy-5-nitropyridine was formed together with 2-methylpropene.