127792-75-0 Usage
Uses
CP 93129 dihydrochloride is a 5HT1B agonist.
Biological Activity
Potent and highly selective 5-HT 1B agonist.
Check Digit Verification of cas no
The CAS Registry Mumber 127792-75-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,7,9 and 2 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 127792-75:
(8*1)+(7*2)+(6*7)+(5*7)+(4*9)+(3*2)+(2*7)+(1*5)=160
160 % 10 = 0
So 127792-75-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H13N3O/c16-11-2-1-10-12(15-11)9(7-14-10)8-3-5-13-6-4-8/h1-3,7,13-14H,4-6H2,(H,15,16)
127792-75-0Relevant articles and documents
3-(1,2,5,6-Tetrahydropyrid-4-yl)pyrrolo[3,2-b]pyrid-5-one: a potent and selective serotonin (5-HT(1B)) agonist and rotationally restricted phenolic analogue of 5-methoxy-3-(1,2,5,6-tetrahydropyrid-4-yl)indole
Macor,Burkhart,Heym,Ives,Lebel,Newman,Nielsen,Ryan,Schulz,Torgersen,Koe
, p. 2087 - 2093 (2007/10/02)
The synthesis and in vitro and in vivo characteristics of 3-(1,2,5,6-tetrahydropyrid-4-yl)pyrrolo[3,2-b]pyrid-5-one (1, CP-93,129) are described. This rotationally restricted phenolic analogue of RU-24,969 is a potent (15 nM) and selective (200x vs the 5-
