127812-08-2

Basic information

• Product Name: 5,10,15,20-TETRAKIS(4-CARBOXYMETHYLOXYPHENYL)-21H,23H-PORPHINE
• Synonyms: 5,10,15,20-TETRAKIS(4-CARBOXYMETHYLOXYPHENYL)-21H,23H-PORPHINE;Tetrakiscarboxymethyloxyphenylporphine;5,10,15,20-Tetrakis(4-carboxymethyloxyphenyl)porphyrin
• CAS NO: 127812-08-2
• Molecular Formula: C₅₂H₃₈N₄O₁₂
• Molecular Weight: 910.88
• Product Categories: Biochemistry;Porphyrins
• Mol File: 127812-08-2.mol

Chemical Properties

• Appearance: /
• Density: 1.443g/cm³
• Refractive Index: 1.687
• CAS DataBase Reference: 5,10,15,20-TETRAKIS(4-CARBOXYMETHYLOXYPHENYL)-21H,23H-PORPHINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5,10,15,20-TETRAKIS(4-CARBOXYMETHYLOXYPHENYL)-21H,23H-PORPHINE(127812-08-2)
• EPA Substance Registry System: 5,10,15,20-TETRAKIS(4-CARBOXYMETHYLOXYPHENYL)-21H,23H-PORPHINE(127812-08-2)

Safety Data

• Hazardous Substances Data: 127812-08-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5,10,15,20-TETRAKIS(4-CARBOXYMETHYLOXYPHENYL)-21H,23H-PORPHINE is used as a coordination compound for its anti-tumor properties. It has been utilized in the formation of 109Pd-porphyrin complexes, which exhibit potential anti-cancer activities. These complexes can modulate various oncological signaling pathways, potentially leading to the inhibition of tumor growth and progression.
Used in Material Science:
In the field of material science, 5,10,15,20-TETRAKIS(4-CARBOXYMETHYLOXYPHENYL)-21H,23H-PORPHINE is used in the preparation of catechol-functionalized zinc oxide nanorod/porphyrin assemblies. These assemblies can be employed in various applications, such as in the development of advanced materials with enhanced properties, including improved optical, electronic, or catalytic performance.

InChI:InChI=1/C52H38N4O12/c57-45(58)25-65-33-9-1-29(2-10-33)49-37-17-19-39(53-37)50(30-3-11-34(12-4-30)66-26-46(59)60)41-21-23-43(55-41)52(32-7-15-36(16-8-32)68-28-48(63)64)44-24-22-42(56-44)51(40-20-18-38(49)54-40)31-5-13-35(14-6-31)67-27-47(61)62/h1-24,53,56H,25-28H2,(H,57,58)(H,59,60)(H,61,62)(H,63,64)/b49-37-,49-38-,50-39-,50-41-,51-40-,51-42-,52-43-,52-44-

Upstream product

• 106456-81-9 meso-tetrakis<4-(allyloxy)phenyl>porphyrin 
• 127812-10-6 5,10,15,20-tetra(4′-carboethoxymethyleneoxyphenyl)porphyrin 
• 51094-17-8 5,10,15,20-tetrakis(4'-hydroxyphenyl)porphyrin 
• 79-11-8 chloroacetic acid 
• 51264-69-8 ethyl 2-(4-formylphenoxy)acetate 
• 123-08-0 4-hydroxy-benzaldehyde 
• 22042-71-3 (4-formylphenoxy)acetic acid 
• 73620-18-5 methyl (4-formylphenoxy)acetate 

Relevant articles and documents

A stable single piece of unimolecularly π-stacked porphyrin aggregate in a thixotropic low molecular weight gel: A one-dimensional molecular template for polydiacetylene wiring up to several tens of micrometers in length

An amide-type copper porphyrin gelator having alkyldiacetylene tethers gives very transparent gel in Decalin, and the gel shows unique thixotropic behavior. One-dimensional aggregates generated in the gel act as templates for unimolecularly segregated pol

Studies towards elucidating the potential of 5,10,15,20-tetrakis(: P -carboxy-methyleneoxyphenyl)porphyrin as a theranostic agent for applications in PET and PDT

Porphyrins, owing to their inherent tendency to accumulate in tumorous lesions, are considered suitable for developing agents for theranostic applications involving tumor diagnosis and targeted tumor therapy. The aim of the present work is to study the po

Designs, synthesis, characterization and direct electrochemistry of zinc-porphyrin bearing pyrene noncovalent functionalized graphene oxide sheet

We have designed and synthesis a new compound of zinc-porphyrin bearing four pyrene groups (ZnP-t-P(py)4) and prepared a new hybrid materials of ZnP-t-P(py)4 with graphene oxide (GO) via non-covalent interactions. The ZnP-t-P(py)sub

Flexible porphyrin tetracarboxylic acids for crystal engineering

Tetrakis[4-(carboxymethyleneoxy)phenyl]porphyrin, a flexible tetraacid ligand, is a new attractive building block for the formulation of coordination polymers and hydrogen bonding supramolecular assemblies in the solid state.

A new synthesis of meso-tetra[4-(carboxymethylenoxy)phenyl]porphyrin

A new convenient synthetic method is reported for meso- tetra[4(carboxymethylenoxy)phenyl]-porphyrin (TCMOPPH2) comprising two steps from meso-tetra(4-hydroxyphenyl)porphyrin nickel (THPPNi) and monochloroacetic acid. The product was characterized by Uv-Vis, IR, and 1HNMR spectra.

Layer-by-Layer Assemblies of Catechol-Functionalized TiO2 Nanoparticles and Porphyrins through Electrostatic Interactions

In the current work, we present the successful functionalization and stabilization of P-25 TiO2 nanoparticles by means of N1,N7-bis(3-(4-tert-butyl-pyridium-methyl)phenyl)-4-(3-(3-(4-tert-butyl-pyridinium-methyl)phenylamino)-3-oxopropyl)-4-(3,4

Porphyrin synthesis in surfactant solution: Multicomponent assembly in micelles

A synthesis of meso-substituted porphyrins in anionic sodium dodecyl sulfate micelles has been developed. Polar, functionalized aromatic aldehydes condense reversibly with pyrrole in the micellar phase. Oxidation of the porphyrinogen then provides functionalized porphyrins in yields of 10-48%. Hydrophobic aldehydes condense irreversibly to give low yields at practical substrate concentrations. Synthesis in D2O solution results in per-β-deuterated porphyrins. A two-phase model is used to rationalize the dependence of porphyrin yield on reactant and surfactant concentration. Micelles are viewed as potential wells which promote porphyrinogen assembly by binding products more tightly than reactants.

SYNTHESIS OF TETRAPHENYLPORPHINES WITH ACTIVE GROUPS IN THE PHENYL RINGS. 5. TETRA(CARBOXYMETHYLENOXYPHENYL)PORPHINES AND THEIR ETHYL ESTERS.

Tetra(carboxymethylenoxyphenyl)porphines which are soluble in bases are prepared by hydrolysis of the ethyl esters of tetra(carboxymethylenoxyphenyl)porphines.The starting ethyl esters of the tetra(carboxymethylenoxyphenyl)porphines were synthesized by alkylation of tetra(oxyphenyl)porphines with ethylchloroacetate, as well as by condensation of pyrrole with ethyl esters of formylphenoxyacetic acids.