51264-69-8

Usage

Uses

Used in Pharmaceutical Industry:
4-Formylphenoxyacetic acid ethyl ester is used as a building block for the synthesis of various pharmaceutical compounds. Its versatile chemical structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
4-Formylphenoxyacetic acid ethyl ester is used as a precursor in the synthesis of agrochemicals, such as pesticides and herbicides. Its ability to form stable compounds in various organic solvents makes it a valuable component in the development of effective and environmentally friendly agrochemical products.
Used in Chemical Research:
4-Formylphenoxyacetic acid ethyl ester is used as a research chemical for studying the properties and reactions of esters in organic chemistry. Its solubility and stability in various solvents make it an ideal candidate for investigating the behavior of ester compounds in different chemical environments.

InChI:InChI=1/C11H12O4/c1-2-14-11(13)8-15-10-5-3-9(7-12)4-6-10/h3-7H,2,8H2,1H3

Upstream product

• 123-08-0 4-hydroxy-benzaldehyde 
• 105-36-2 ethyl bromoacetate 
• 1609-47-8 diethyl dicarbonate 
• 22042-71-3 (4-formylphenoxy)acetic acid 
• 105-39-5 chloroacetic acid ethyl ester 
• 104-15-4 toluene-4-sulfonic acid 
• 79-08-3 bromoacetic acid 
• 65079-45-0 [4-(hydroxyimino-methyl)-phenoxy]-acetic acid ethyl ester 
• 64-17-5 ethanol 

Downstream Products

• 24634-65-9 [4-(trans-2-nitro-vinyl)-phenoxy]-acetic acid ethyl ester 
• 101734-69-4 (α'-nitro-cis-stilben-4-yloxy)-acetic acid ethyl ester 
• 67839-24-1 [4-(4-oxo-[1,3]thiazinan-2-yl)-phenoxy]-acetic acid ethyl ester 
• 67839-42-3 [4-(4-oxo-3,4-dihydro-2H-benzo[e][1,3]thiazin-2-yl)-phenoxy]-acetic acid ethyl ester 
• 127812-10-6 5,10,15,20-tetra(4′-carboethoxymethyleneoxyphenyl)porphyrin 
• 98314-72-8 {2-[(E)-3-(4-Carboxymethoxy-phenyl)-acryloyl]-5-hydroxy-phenoxy}-acetic acid 
• 107045-07-8 Ethyl 4-(3-methyl-5-oxo-pyrazolidenemethyl)-phenoxyacetate 
• 101734-69-4 α-Nitro-4'-carbaethoxymethoxy-stilben 
• 72668-64-5 ethyl [4-(1,3-dioxolan-2-yl)phenoxy]acetate 
• 65079-45-0 [4-(hydroxyimino-methyl)-phenoxy]-acetic acid ethyl ester 
• 875801-89-1 {4-[(E)-2-(1,3-Dimethyl-5-nitro-2,6-dioxo-1,2,3,6-tetrahydro-pyrimidin-4-yl)-vinyl]-phenoxy}-acetic acid ethyl ester 
• 847375-27-3 5-(4′-carboethoxymethyleneoxyphenyl)dipyrromethane 
• 916804-58-5 5-[4-(ethoxycarbonylmethoxy)phenyl]-1,9-diformyldipyrromethane 
• 926622-31-3 5-[4-(ethoxycarbonylmethoxy)phenyl]-1,9-bis(N-propylimino)dipyrromethane 

Relevant academic research and scientific papers

EBNA1-specific luminescent small molecules for the imaging and inhibition of latent EBV-infected tumor cells

An EBNA1-specific small molecule (JLP2) has been synthesised. As a strong binder and dimerization inhibitor of EBNA1 in vitro, JLP2 may be used as a selective luminescent agent for the imaging and inhibition of latent EBV-infected ca

Organic nanoparticles of acetohydrazides as novel inhibitors for mild steel corrosion

Novel organic nanoparticles (ONPs) of (E)-2-(4-(hydrazonomethyl)phenoxyl) acetohydrazide (H2) and N′((E)-benzylidene)-2-(4-((E)hydrazonomethyl)phenoxyl)acetohydrazide (H3) were prepared by the re-precipitation method. The ONPs were characterized using MS,

PhotoTag: Photoactivatable Fluorophores for Protein Labeling

We report experimental studies on the development of photoactivatable fluorophores for rapid, light-induced synthesis of protein conjugates. Proof-of-concept studies demonstrated that electronic excitation of photoactivatable BODIPY-ArN3 (1) in

Computational de novo design and characterization of a four-helix bundle protein that selectively binds a nonbiological cofactor

We report the complete de novo design of a four-helix bundle protein that selectively binds the nonbiological DPP-Fe(III) metalloporphyrin cofactor (DPP-Fe(III) = 5, 15-Di[(4-carboxymethyleneoxy)phenyl]porphinato iron(III)). A tetrameric, D2-sy

Synthesis and antinociceptive profile of novel acidic sulphonylhydrazone derivatives from natural safrole

The synthesis and antinociceptive activity of new sulphonylhydrazone derivatives is described. The synthetic route started from safrole, an abundant Brazilian natural product which occurs in sassafras oil (Ocotea pretiosa). The active compounds were obtai

Photophysical and bactericidal properties of pyridinium and imidazolium porphyrins for photodynamic antimicrobial chemotherapy

Despite advances achieved over the last decade, infections caused by multi-drug-resistant bacterial strains are increasingly becoming important societal issues that need to be addressed. New approaches have already been developed in order to overcome this problem. Photodynamic antimicrobial chemotherapy (PACT) could provide an alternative to fight infectious bacteria. Many studies have highlighted the value of cationic photosensitizers in order to improve this approach. This study reports the synthesis and the characterization of cationic porphyrins derived from methylimidazolium and phenylimidazolium porphyrins, along with a comparison of their photophysical properties with the well-known N-methylpyridyl (pyridinium) porphyrin family. PACT tests conducted with the tetracationic porphyrins of these three families showed that these new photosensitizers may offer a good alternative to the classical pyridinium porphyrins, especially against S.aureus and E.coli. In addition, they pave the way to new cationic photosensitizers by the means of derivatization through amide bond formation.

Fluorescent multi-component polymer sensors for the sensitive and selective detection of Hg2+/Hg+ions: Via dual mode fluorescence and colorimetry

Multi-component polymers (MCPs) incorporate multiple components into the main chain or pendant group and have special functions. In this work, the small-molecule fluorescent boron-dipyrromethene (BODIPY), with ester groups and/or alkoxyl long chains, was synthesized first. Then, this small-molecule BODIPY and the components containing CC bonds (HD and PD) were reacted via the Heck coupling reaction to obtain macromolecular probes that perform different functions. With the help of ester groups and alkoxyl "tail", polymers MCP1 and MCP2 were soluble in a variety of water-miscible organic solvents. Moreover, MCP3 and MCP4 were completely soluble in water. These macromolecular probes showed sensitive and selective recognition toward Hg2+/Hg+ because of the introduced components (HD and PD) containing CC bonds. After binding to Hg2+/Hg+, MCP1 and MCP2 demonstrated fluorescence quenching and color changes, which allowed the dual-channel specific detection of Hg2+/Hg+. Compared with the probes containing HD, the probes containing PD showed higher sensitivity, and the good recognition ability caused the detection limit to be as low as 0.32 μM, which may be due to the "molecular wire"mechanism. The small-molecule components with different functional groups were polymerized into fluorescent polymer materials. This methodology endows the polymer probe with good solubility and high sensitivity, and the as-prepared polymers could sense metal ions in aqueous environments. This journal is

Microwave-assisted efficient synthesis of pyrazole-fibrate derivatives as stimulators of glucose uptake in skeletal muscle cells

The design and synthesis of a series of pyrazolo[3,4-d]pyrimidinones containing fibrate side chains have been accomplished by utilizing the concept of molecular hybridization. All the synthesized compounds were evaluated for the glucose uptake stimulatory effect in L6 rat skeletal muscle cells. Four compounds (3f, 3g, 3j and 3q) were found to show significant stimulation of glucose uptake. Further these four compounds have been examined for their Glut4 translocation stimulatory effect in L6-Glut4myc myotubes. Compound 3q was found to exert maximum increase in GLUT4myc translocation.

Acylhydrazone derivative containing phosphonate and preparation method and application thereof

The invention discloses an acylhydrazone derivative containing phosphonate and a preparation method and application thereof. The structural general formula of the acylhydrazone derivative containing phosphonate is as shown in the specification. According

Micellar Br?nsted Acid Mediated Synthesis of DNA-Tagged Heterocycles

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