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1278540-65-0

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1278540-65-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1278540-65-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,7,8,5,4 and 0 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1278540-65:
(9*1)+(8*2)+(7*7)+(6*8)+(5*5)+(4*4)+(3*0)+(2*6)+(1*5)=180
180 % 10 = 0
So 1278540-65-0 is a valid CAS Registry Number.

1278540-65-0Downstream Products

1278540-65-0Relevant articles and documents

Design and synthesis of indomethacin analogues that inhibit P-glycoprotein and/or multidrug resistant protein without Cox inhibitory activity

Arisawa, Mitsuhiro,Kasaya, Yayoi,Obata, Tohru,Sasaki, Takuma,Nakamura, Tomonori,Araki, Takuya,Yamamoto, Koujirou,Sasaki, Akito,Yamano, Akihito,Ito, Mika,Abe, Hiroshi,Ito, Yoshihiro,Shuto, Satoshi

, p. 8152 - 8163 (2012/11/07)

We designed and synthesized conformationally restricted analogues and regioisomers of the nonsteroidal anti-inflammatory drug indomethacin. Evaluation of the inhibitory effects of these compounds on COX, P-glycoprotein, and multidrug resistance indicated that NSAIDS modulation of multidrug-resistant P-glycoprotein and multidrug-resistant protein-1 is not associated with COX-1 and COX-2 inhibitory activities.

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