127896-08-6

Basic information

• Product Name: Carbamic acid, 2-propynyl-, 9H-fluoren-9-ylmethyl ester
• CAS NO: 127896-08-6
• Molecular Formula: C18H15NO2
• Molecular Weight: 277.323
• Mol File: 127896-08-6.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: Carbamic acid, 2-propynyl-, 9H-fluoren-9-ylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, 2-propynyl-, 9H-fluoren-9-ylmethyl ester(127896-08-6)
• EPA Substance Registry System: Carbamic acid, 2-propynyl-, 9H-fluoren-9-ylmethyl ester(127896-08-6)

Safety Data

• Hazardous Substances Data: 127896-08-6(Hazardous Substances Data)

Upstream product

• 28920-43-6 (fluorenylmethoxy)carbonyl chloride 
• 15430-52-1 prop-2-yn-1-amine hydrochloride 
• 102774-86-7 9-fluorenylmethyl N-succinimidyl carbonate 
• 2450-71-7 Propargylamine 
• 82911-69-1 N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide 

Downstream Products

• 1357309-72-8 4-(3-(tert-butoxy)-3-oxopropyl)-2,6-diisopropylphenyl 7-(4-(((((9H-fluoren-9-yl)methoxy)carbonyl)amino)methyl)-1H-1,2,3-triazol-1-yl)-4-oxoheptanoate 
• 1357309-74-0 4-(3-((2,5-dioxopyrrolidin-1-yl)oxy)-3-oxopropyl)-2,6-di-isopropylphenyl 7-(4-(((((9H-fluoren-9-yl)methoxy)carbonyl)-amino)methyl)-1H-1,2,3-triazol-1-yl)-4-oxoheptanoate 
• 1256164-17-6 C₂₃H₂₁N₅O₂ 
• 1285712-71-1 C₂₇H₂₅N₅O₃ 
• 1005496-73-0 C₃₂H₃₀NO₅P 
• 1005496-72-9 (9H-fluoren-9-yl)methyl 2-((benzyloxy)phosphono)allylcarbamate 
• 736175-81-8 C₂₈H₂₁⁽²⁾H₈NO₄ 
• 943918-75-0 N-Fmoc-(4-(aminomethyl)-triazol-1-yl) benzyl acetate 

Relevant articles and documents

Synthesis of the middle fragment of oxazolomycin

A stereoselective and direct synthesis of an (E,E)-diene suitable for application to the synthesis of oxazolomycin and its analogues is reported.

Synthesis and characterization of the 7-(4-aminomethyl-1H-1,2,3-triazol-1- yl) analogue of kabiramide C

The 7-(4-aminomethyl-1H-1,2,3-triazol-1-yl) analogue of kabiramide C (5) was synthesized by using the Mitsunobu reaction and 1,3-dipolar cycloaddition. This compound and the intermediate compounds 2 and 4 were shown to bind tightly to G-actin in a 1:1 complex and exhibited the same degree of cytotoxicity as 1. Compound 5 serves as a key intermediate for the synthesis of actin-directed optical probes and drugs.

A heterocyclic peptide nanotube

An open-ended hollow tubular structure is designed based on hydrogen-bond-directed self-assembly of a chimeric cyclic peptide subunit comprised of alternating α- and ε-amino acids. The design features a novel 1,4-disubstituted-1,2,3-triazole ε-amino acid

Functionalized triazolopeptoids-a novel class for mitochondrial targeted delivery

Here we introduce linear 1,4-triazolopeptoids as a novel class of cell penetrating peptidomimetics suitable as organ targeting molecular transporters of bioactive cargo. Repetitive triazole moieties with up to three residues were assembled on solid supports using copper-catalyzed alkyne-azide cycloadditions (CuAAC) in a submonomer approach. Depending on the lipophilicity of their side chain appendages the 1,4-triazolopeptoids showed either endosomal localization or a strong colocalization with the mitochondria of HeLa cells with moderate toxicity. While the basic triazolopeptoids mainly target the neuromast cells in zebrafish embryos, the lipophilic ones colocalize with either cartilage in the jaws and the blood vessel system. This journal is