1279129-36-0Relevant academic research and scientific papers
PhI(OAc)2-mediated alkoxyoxygenation of β,γ-unsaturated ketoximes: Preparation of isoxazolines bearing two contiguous tetrasubstituted carbons
Ye, Chenghao,Kou, Xuezhen,Yang, Guoqiang,Shen, Jiefeng,Zhang, Wanbin
, p. 1148 - 1152 (2019)
A PhI(OAc)2-promoted dioxygenation of allyl oximes, including one alkoxylation, has been developed. This reaction can give isoxazoline products bearing two contiguous tetrasubstituted carbons. Various oximes substrates bearing different aryl groups and tetrasubstituted-olefin moieties were compatible with the mild reaction conditions. A two-electron oxidation pathway was proposed based on results of preliminary mechanistic studies.
Tetrasubstituted olefins through the stereoselective catalytic intermolecular conjugate addition of simple alkenes to α,β- unsaturated carbonyl compounds
Kwon, Ki-Hyeok,Lee, Do W.,Yi, Chae S.
supporting information; experimental part, p. 1692 - 1695 (2011/04/15)
Branching out: The cationic ruthenium-hydride complex [Ru]+ was found to be a highly effective catalyst precursor for the conjugate addition of unactivated olefins to α,β-unsaturated carbonyl compounds to yield tetrasubstituted olefins. A kinetic analysis provides support for the mechanism involving a regioselective olefin insertion and rapid alkene isomerization steps.
