128229-81-2Relevant academic research and scientific papers
Br?nsted Acid Enabled Nickel-Catalyzed Hydroalkenylation of Aldehydes with Styrene and its Derivatives
Han, Xing-Wang,Zhang, Tao,Zheng, Yan-Long,Yao, Wei-Wei,Li, Jiang-Fei,Pu, You-Ge,Ye, Mengchun,Zhou, Qi-Lin
supporting information, p. 5068 - 5071 (2018/03/27)
A Br?nsted acid enabled nickel-catalyzed hydroalkenylation of aldehydes and styrene derivatives has been developed. The Br?nsted acid acts as a proton shuttle to transfer a proton from the alkene to the aldehyde, thereby leading to an economical and byproduct-free coupling. A series of synthetically useful allylic alcohols were obtained through one-step reactions from readily available styrene derivatives and aliphatic aldehydes in up to 88 % yield and with high linear selectivity.
Convergent synthesis of conjugated 1,2-disubstituted E-allylic alcohols from two aldehydes and methylenetriphenylphosphorane
Hodgson, David M.,Persaud, Rosanne S. D.
supporting information, p. 7949 - 7951 (2013/06/27)
β-Lithiooxyphosphonium ylides, made in situ from an aldehyde and methylenetriphenylphosphorane, react with a second aldehyde to form E-allylic alcohols. α-Branching and α,β-unsaturation in the second aldehyde, together with the lack of further substitution on the phosphorane carbon play important roles in selectivity. A range of these aldehydes, in addition to aromatic aldehydes as the second aldehyde also provided synthetically useful access to E-allylic alcohols.
Facile enantioselective synthesis of 6R-(+)-goniothalamin and (6R, 7R, 8R)-(+)-goniothalamin oxide
Peng, Xiaoshui,Li, Anpai,Shen, Hao,Wu, Tongxing,Pan, Xinfu
, p. 330 - 332 (2007/10/03)
Facile enantioselective total syntheses of 6R-(+)-goniothalamin 1 and (6R, 7R, 8R)-(+)-goniothalamin oxide 2 were achieved through the Sharpless kinetic resolution of racemic secondary 2- furylmethanol 3 in a short synthetic route.
Enantioselective Syntheses of (+)-Acetylphomalactone and (6R)-(+)-Goniothalamin from 2-Furylmethanols
Honda, Toshio,Kametani, Tetsuji,Kanai, Kazuo,Tatsuzaki, Yoko,Tsubuki, Masayoshi
, p. 1733 - 1737 (2007/10/02)
Enantioselective syntheses of two 6-substituted 5,6-dihydro-2H-pyran-2-ones, (+)-acetylphomalactone and (6R)-(+)-goniothalamin, are described which use the kinetic resolution of racemic secondary 2-furylmethanols.
