128348-23-2Relevant academic research and scientific papers
4-Substituted thiophene- and furan-2-sulfonamides as topical carbonic anhydrase inhibitors
Hartman,Halczenko,Smith,Sugrue,Mallorga,Michelson,Randall,Schwam,Sondey
, p. 3822 - 3831 (1992)
A series of 4-substituted thiophene- and furan-2-sulfonamides was prepared and was found to possess nanomolar-level potency for inhibition of human carbonic anhydrase II in vitro. Selected examples from this group were further evaluated for their potentia
POTENTIAL ANTIDEPRESSANTS AND INHIBITORS OF 5-HYDROXYTRYPTAMINE AND NORADRENALINE RE-UPTAKE IN THE BRAIN: N,N-DIMETHYL-(ARYLTHIO)THENYLAMINES AND N,N-DIMETHYL-2-(THIENYLTHIO)BENZYLAMINES
Sindelar, Karel,Pomykacek, Josef,Valchar, Martin,Dobrovsky, Karel,Metysova, Jirina,Polivka, Zdenek
, p. 449 - 458 (2007/10/02)
3-(3-Methoxyphenylthio)thiophene-2-carboxylic acid (IV) and 2-(3-methoxyphenylthio)thiophene-3-carboxylic acid (VII) were transformed via acid chlorides and dimethylamides to the amines V and VIII which were demethylated to the phenolic amines VI and IX.N
