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Upstream product

• 1008-89-5 2-phenylpyridine 
• 10025-99-7 potassium tetrachloroplatinate(II) 
• 155475-93-7 phenylpyridinebridgedichloro platinum 
• 155311-84-5 Pt(2-phenylpyridinate)Cl(DMSO) 

Downstream Products

• 1440970-58-0 ClO₄^(1-)*C₄₇H₃₈N₅PtS₃⁽¹⁺⁾ 

Relevant academic research and scientific papers

Encapsulation of multi-stimuli AIE active platinum(II) complex: A facile and dry approach for luminescent mesoporous silica

Luminescent materials have great potential in diverse applications in their solid state. Because these materials are subject to the aggregation-caused quenching (ACQ) effect, increasing attention is focused on synthesizing aggregation-induced emission (AIE) active materials to avoid the ACQ effect. Herein a new class of AIE active, excimeric platinum(ii) complex, [Pt(C^N)(L1)(Cl)], 3 [C^N = 2-phenylpyridine; L1 = N1-tritylethane-1,2-diamine] is reported. The complex 3 exhibited mechanofluorochromism (MFC) and thereby transformed into an orange-emitting complex, 3a, upon grinding. Crushing of 3 (or 3a) with meso-structured silica produced a luminescent composite material, 3b, and thereby the AIE Pt(ii) complex moved into the mesopores and the process signaled with a drastic change of emission color (yellow → green). The solid-state luminescent behaviour of these complexes was thoroughly studied. The photophysical properties were also supported by TD-DFT based theoretical study.

Synthesis, characterization and photophysical properties of new cyclometallated platinum(II) complexes with pyrazolonate ancillary ligand

New cyclometalated platinum(II) complexes with pyrazolonate ancillary ligand (ppy)Pt(pmip) (1) and (dfppy)Pt(pmip) (2) (ppy = 2-phenylpyridine, dfppy = (4,6-difluorophenyl)pyridine, Hpmip = 1-phenyl-3-methyl-4-isobutyryl-5- pyrazolone) were synthesized and structurally characterized. Both compounds revealed square-planar geometry. The crystal cell of 1 was found to contain the monomer molecules of platinum compound whereas dimer molecules of 2 with short Pt?Pt contacts of 3.2217(3) were observed in the crystal cell of 2. Photophysical properties of 1 and 2 were investigated in detail. The highly resolved photoluminesence spectra of the platinum complexes in solution contain emission bands in the region of 470-550 nm attributed to monomer compounds 1 and 2. The triplet-state energies of 1 and 2 obtained from DFT calculations agree very well with the experimental data. In the crystalline state complex 2 revealed excimer emission as a structureless broad band at ca. 584 nm related to dimer molecules of platinum compound presented in the crystals.

Anionic cyclometalated Pt(ii) and Pt(iv) complexes respectively bearing one or two 1,2-benzenedithiolate ligands

Novel anionic cyclometalated Pt(ii) square-planar complexes NBu4[(C^N)PtII(S^S)], containing 2-phenylpyridine H(PhPy), 2-(2,4-difluorophenyl)-pyridine H(F2PhPy) and benzo[h]quinoline H(Bzq), respectively, as a cyclometalated ligand and the dianionic 1,2-benzenedithiolate (Thio)2- fragment as an (S^S) ligand, were synthesised. By the simple addition of an equivalent of (Thio)2- to the NBu4[(C^N)PtII(Thio)] complexes, octahedral anionic NBu4[(C^N)PtIV(Thio)2] analogues were obtained, representing, to the best of our knowledge, the first examples of Pt(iv) anionic cyclometalated complexes. The molecular structures of the obtained complexes in the case of the NBu4[(Bzq)PtII(Thio)] and the NBu4[(Bzq)PtIV(Thio)2] complexes were confirmed by single crystal X-ray diffraction analysis. Furthermore, the electrochemical and photophysical properties of the two series of Pt(ii) and Pt(iv) newly synthesised complexes were studied and DFT and TD-DFT calculations were performed in order to comprehensively investigate the displayed behaviour. All Pt(ii) and Pt(iv) complexes show intense luminescence in the solid state, with remarkable enhancement of the emission quantum yields, proving to be excellent examples of aggregation-induced emission systems.

Appended aromatic moieties determine the cytotoxicity of neutral Cyclometalated Platinum(II) complexes derived from 2-(2-Pyridyl)benzimidazole

A new family of neutral chiral cyclometalated platinum(II) complexes with formula [Pt(κ2-(C^N))Cl(κ1-(L))], where (C^N) = 2-phenylpyridinate and (L) = 2-(2-pyridyl)benzimidazole (L1) or (N-(CH2)-Ar-(2-(2-pyridyl)benzimidazole) ligands; (Ar = phenyl (L2), naphthyl (L3), pyrenyl (L4)), have been synthesized and completely characterized. The unexpected κ1 coordination mode of the 2-(2-pyridyl)benzimidazole-derived ligands has been confirmed by spectroscopic techniques and X-ray diffraction. The aromatic moieties on the ligands in the new platinum(II) complexes have a remarkable influence on the cytotoxicity and in the binding mode to DNA. [Pt-L1]-[Pt-L4] complexes internalized more than cisplatin in the SW480 cancer cells even though only [Pt-L1] and [Pt-L2] display high cytotoxicity. 1H NMR and 13P{1H}NMR pointed out that [Pt-L1] and [Pt-L2] complexes bind covalently to dGMP, while the electrophoresis assays and CD experiments indicate that only [Pt-L2] is able to covalently interact with DNA, inducing the same conformational changes in the plasmid DNA as cisplatin. Although the complex [Pt-L4] intercalates into DNA, probably through the pyrenyl moiety, no biological activity is observed.

Water soluble luminescent cyclometalated platinum(II) complex - A suitable probe for bio-imaging applications

A highly water soluble platinum(II) complex, [Pt(ppy)(en)]Cl, (where ppy = 2-phenylpyridine and en = ethane-1, 2-diamine) with a strong green luminescence in solution was synthesized in two steps. Initially, an intermediate complex, [Pt(ppy)(ppyH)(Cl)], 1 was isolated which was transformed into the light-emitting mononuclear platinum(II) complex, [Pt(ppy)(en)]Cl, 2. The green emission of 2 was changed into yellow in their solid state. The strong π?π intermolecular interactions that interplays between the phenyl rings lying into the two consecutive molecules which led to the solid state emission. The low cytotoxicity of 2 ensures the feasibility for using these in bioimaging probe. The testing bioimaging results demonstrate that the compound penetrates the cell membrane in both cancer (HeLa, U87MG and Nuro2a) and normal cells (CHO-K1 and 3T3-L1). The cellular uptake was observed to much higher in cancerous cells only. Co-localization study confirmed the localization of it into the cell nucleus.

Rare observation of 'aggregation induced emission' in cyclometalated platinum(ii) complexes and their biological activities

Three strong solid state emissive cyclometalated platinum(ii) complexes [Pt(C^N) (CH^N) (Cl)] (1) (C^N/CH^N = 2-phenylpyridine, C^N = bidentate and CH^N = monodentate), [Pt(C^N) (P^P)]Cl [P^P = bis(diphenylphosphino)ethane (2) and cis-1,2-bis(diphenylphos

ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES

The present invention discloses novel Pt(IV) compounds useful for enhancing the performance of organic electroluminescent devices.

Protein staining agents from low toxic platinum(II) complexes with bidentate ligands

Three new luminescent platinum(ii) complexes with bidentate C^N and O^O ligands have been designed and synthesized in this work. Along with the changing of C^N ligands, the emission peaks of these complexes range from 489 to 629 nm and the photoluminescen

Synthesis, structures and spectroscopic properties of platinum complexes containing orthometalated 2-phenylpyridine

The synthesis, structure and spectroscopy of a series of luminescent orthometalated square planar platinum(II) complexes are reported. Reaction of K2PtCl4 with one mole equivalent of 2-phenylpyridine (ppyH) in 2-ethoxyethanol and water (1:1 ratio) resulted in the formation of chloro-bridged dimeric precursor [Pt2(μ-Cl)2(ppy)2], which on further reactions with various anionic one-, two- and three-atom ancillary ligands, having O/N/S donors, yielded mono- and bi-nuclear platinum(II) complexes. Platinum(III) complexes of composition [Pt2Cl2(μ-Epy)2(ppy)2] have been isolated with pyE- (E = O or S) ligands. These complexes have been characterized by elemental analysis, NMR (1H, 31P, 195Pt) and absorption spectroscopy. The complexes [Pt2(μ-N∩N)2(ppy)2] (N∩N = pyrazole and 3,5-dimethylpyrazole); [Pt(S∩S)(ppy)] (S∩S = ethylxanthate and diisopropyldithiophosphate); [Pt2Cl2(μ-Epy)2(ppy)2] (Epy = 2-pyridinol {Opy} and 2-mercaptopyridine {Spy}) and [PtCl(ppy)(PhNC(Me)NHPh)] have been structurally characterized by X-ray crystallography.

Synthesis and characterization of luminescent bis-cyclometalated platinumIV complexes

Presented is the synthesis and characterization of a series of luminescent heteroleptic bis-cyclometalated platinumIV complexes. An oxidation-facilitated cyclometalation is employed to convert platinum II pendant species into bis-cyc