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128495-45-4

128495-45-4

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128495-45-4 Usage

Synthesis Reference(s)

Journal of Medicinal Chemistry, 33, p. 2408, 1990 DOI: 10.1021/jm00171a014

Check Digit Verification of cas no

The CAS Registry Mumber 128495-45-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,8,4,9 and 5 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 128495-45:
(8*1)+(7*2)+(6*8)+(5*4)+(4*9)+(3*5)+(2*4)+(1*5)=154
154 % 10 = 4
So 128495-45-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H9FO2/c1-11-8-4-6(5-10)2-3-7(8)9/h2-4,10H,5H2,1H3

128495-45-4 Well-known Company Product Price

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  • Alfa Aesar

  • (H31897)  4-Fluoro-3-methoxybenzyl alcohol, 95%   

  • 128495-45-4

  • 1g

  • 277.0CNY

  • Detail

  • Alfa Aesar

  • (H31897)  4-Fluoro-3-methoxybenzyl alcohol, 95%   

  • 128495-45-4

  • 10g

  • 1681.0CNY

  • Detail

128495-45-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Fluoro-3-Methoxybenzyl Alcohol

1.2 Other means of identification

Product number -
Other names (4-Fluoro-3-methoxyphenyl)methanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:128495-45-4 SDS

128495-45-4Relevant articles and documents

Asymmetric synthesis of fluorinated L-tyrosine and meta-L-tyrosines

Monclus, Michel,Masson, Carine,Luxen, Andre

, p. 39 - 44 (1995)

A convenient asymmetric synthesis of (2S)-2-amino-3-(2-fluoro-5-hydroxyphenyl) propanoic acid, (2S)-2-amino-3-(4-fluoro-3-hydroxyphenyl) propanoic acid and (2S)-2-amino-3-(2-fluoro-4-hydroxyphenyl) propanoic acid is described.Key steps include the synthes

Synthesis and Biological Evaluation of 1,2,3-triazole tethered Pyrazoline and Chalcone Derivatives

Hussaini, Syed Mohammed Ali,Yedla, Poornachandra,Babu, Korrapati Suresh,Shaik, Thokhir B.,Chityal, Ganesh Kumar,Kamal, Ahmed

, p. 97 - 109 (2016/07/09)

A series of pyrazoline derivatives and corresponding chalcone intermediates with substituents same as combretastatin-A4(CA-4) conjugated with triazole nucleus has been synthesized and evaluated for their anticancer potential. Sulphorhodamine B(SRB) assay indicated compound 12c to be the most active compound from the series with GI50 value of 6.7 μm against the human liver carcinoma cell line HepG2. Interestingly, the intermediate 11c exhibited more promising cytotoxicity demonstrating GI50 value of 1.3 μm against the prostate cancer cell line DU145. Compounds 11c and 12c caused accumulation of cells in G2/M phase and inhibited tubulin polymerization. Furthermore, these compounds reduce the mitochondrial membrane potential and activate caspases 3 and 9, thereby indicating their ability to trigger apoptosis.

COMPOUND OF CAMPTOTHECIN AND PREPARATION AND USE THEREOF

-

Paragraph 0218; 0219, (2015/06/24)

The present disclosure relates to a compound of formula I, a pharmaceutical composition thereof and the use thereof as an anti-tumor drug.

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