82846-18-2

Basic information

• Product Name: 4-FLUORO-3-METHOXYBENZOIC ACID
• Synonyms: 4-Fluoro-m-anisic acid, 5-Carboxy-2-fluoroanisole;Fluoro-3-methoxy-benzoic acid;RARECHEM AL BO 0973;4-FLUORO-3-METHOXYBENZOIC ACID;3-METHOXY-4-FLUOROBENZOIC ACID;BUTTPARK 14\01-28;4-Fluoro-3-methoxybenzoic;4-fluoro-m-anisic acid
• CAS NO: 82846-18-2
• Molecular Formula: C₈H₇FO₃
• Molecular Weight: 170.14
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Carboxylic Acids;Phenyls & Phenyl-Het;Acids & Esters;Anisoles, Alkyloxy Compounds & Phenylacetates;Fluorine Compounds;Carboxylic Acids;Phenyls & Phenyl-Het;Fluorine series
• Mol File: 82846-18-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 206 °C
• Boiling Point: 304.8 °C at 760 mmHg
• Flash Point: >110℃
• Appearance: white to light yellow crystal powder
• Density: 1.307 g/cm³
• Vapor Pressure: 0.000376mmHg at 25°C
• Refractive Index: 1.524
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.02±0.10(Predicted)
• BRN: 4178071
• CAS DataBase Reference: 4-FLUORO-3-METHOXYBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-FLUORO-3-METHOXYBENZOIC ACID(82846-18-2)
• EPA Substance Registry System: 4-FLUORO-3-METHOXYBENZOIC ACID(82846-18-2)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-36:37/38-22
• Safety Statements: 26-36-37
• Hazardous Substances Data: 82846-18-2(Hazardous Substances Data)

Usage

Chemical Properties

White to light yellow crystal powder

InChI:InChI=1/C8H7FO3/c1-12-7-4-5(8(10)11)2-3-6(7)9/h2-4H,1H3,(H,10,11)

Upstream product

• 51446-31-2 4-fluoro-3-hydroxybenzoic acid 
• 452-84-6 3-amino-4-fluorotoluene 
• 74385-37-8 methyl 4-fluoro-3-methoxy-benzoate 
• 63762-79-8 2-fluoro-5-methylphenol 
• 63762-78-7 1-fluoro-2-methoxy-4-methylbenzene 

Downstream Products

• 74385-37-8 methyl 4-fluoro-3-methoxy-benzoate 
• 1259307-94-2 tert-butyl 9-(4-fluoro-3-methoxybenzoyl)-3,9-diazaspiro[5.5]undecane-3-carboxylate 
• 1607024-71-4 ethyl 3-(4-fluoro-3-methoxyphenyl)-3-oxopropanoate 
• 1607023-29-9 5-(4-fluoro-3-methoxyphenyl)-3-(1-methyl-1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one 
• 905994-27-6 6-fluoro-7-methoxyisoquinolin-1(2H)-one 
• 82846-19-3 4-fluoro-3-methoxybenzoyl chloride 
• 128495-45-4 (4-fluoro-3-methoxy-phenyl)methanol 
• 1007455-24-4 5-fluoro-6-methoxyisoindolin-1-one 
• 1269834-31-2 (4-(1H-benzo[d]imidazol-1-yl)-3-methoxyphenyl)carboxylic acid methyl ester 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK

Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibiting PAS Kinase (PASK) activity in a human or animal subject are also provided for the treatment of diseases such as diabetes mellitus.

Pyrimido compounds having antiproliferative activity

Disclosed are novel pyrimido compounds that are selective inhibitors of both KDR and FGFR kinases. These compounds and their pharmaceutically acceptable salts are anti-proliferative agents useful in the treatment or control of solid tumors, in particular breast, colon, lung and prostate tumors. Also disclosed are pharmaceutical compositions containing these compounds and methods of treating cancer.