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Usage

Uses

Used in Pharmaceutical Industry:
(betaS)-beta-methyl-L-tyrosine is used as a precursor for the synthesis of various pharmaceuticals, including antimicrobial agents and anticancer drugs. Its potential in this application is due to its ability to modulate neurotransmitter levels, which could lead to the development of new treatments for a range of conditions.
Used in Neurotransmitter Modulation:
(betaS)-beta-methyl-L-tyrosine is used as a neurotransmitter modulator for the treatment of conditions such as depression and attention deficit hyperactivity disorder (ADHD). Its ability to modulate neurotransmitter levels in the brain makes it a promising candidate for further research and potential therapeutic applications in these areas.

Upstream product

• 132338-27-3 (2R,3R)-2-amino-3-(4-methoxyphenyl)butyric acid 
• 754977-47-4 (2R,3S)-2-Amino-3-(4-methoxy-phenyl)-butyric acid 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 600-18-0 2-Oxobutyric acid 
• 108-95-2 phenol 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 105962-41-2 methyl E-2-benzamido-3-p-methoxyphenyl-2-butanoate 
• 57427-93-7 2-phenyl-4-<α-E-p-methoxyphenylethylidene>-5(4H)-oxazolone 
• 151908-49-5 (3(2S,3R),4R)-3-<2-Azido-3-(4-methoxyphenyl)butyroyl>-4-phenyl-2-oxazolidinone 
• 151800-31-6 (3(3S),4R)-3-<3-(4'-Methoxyphenyl)butanoyl>-4-phenyl-2-oxazolidinone 
• 151800-34-9 (2S,3R)-2-Azido-3-(4-methoxyphenyl)butyric acid 
• 758685-22-2 (2S,3R)-2-Amino-3-(4-methoxy-phenyl)-butyric acid 
• 128707-85-7 (S)-3-[(2R,3S)-2-Azido-3-(4-methoxy-phenyl)-butyryl]-4-benzyl-oxazolidin-2-one 
• 128693-82-3 (3(3R),4S)-4-benzyl-3-<3-(4'-methoxyphenyl)butanoyl>-2-oxazolidinone 

Relevant academic research and scientific papers

Synthesis of (2S,3R)-β-Methyltyrosine Catalyzed by Tyrosine Phenol-Lyase

A one-step enzymatic synthesis of the conformationally restrained tyrosine analog (2S,3R)-β-methyltyrosine is reported. This synthesis extends the preparative chemistry associated with tyrosine phenol-lyase. This β-methyltyrosine derivative was shown to be an efficient protein tyrosine kinase substrate, suggesting that conformational restraint may ultimately be used to enhance tyrosine kinase recognition of substrates.

Side chain methyl substitution in the δ-opioid receptor antagonist TIPP has an important effect on the activity profile

The δ-opioid antagonist H-Tyr-Tic-Phe-Phe-OH (TIPP-OH) or its C- terminal amide analogue was systematically modified topologically by substitution of each amino acid residue by all stereoisomers of the corresponding β-methyl amino acid. The potency and se

Efficient Method for the Total Asymmetric Synthesis of the Isomers of β-Methyltyrosine

α-Amino acids modified at the β-carbon atom can provide topographical constraints when incorporated into a peptide.Such modifications can modulate the physical, chemical, and biological properties of the compound.In order to properly evaluate the effect o

An efficient procedure for the demethylation of aryl-methyl ethers in optically pure unusual amino acids

An efficient procedure was developed for the removal of methyl groups from aryl methyl ethers, without racemization, in derivatives of unusual amino acids that are of significant importance in the design of highly selective peptide protein ligands with sp

ASYMMETRIC SYNTHESIS OF UNUSUAL AMINO ACIDS: SYNTHESIS OF OPTICALLY PURE ISOMERS OF β-METHYLTYROSINE

Synthesis of optically pure isomers of β-methyltyrosine has been accomplished.