128612-45-3

Basic information

• Product Name: 1,3-benzodioxol-5-yl methanesulfonate
• Synonyms: 1,3-benzodioxol-5-yl methanesulfonate
• CAS NO: 128612-45-3
• Molecular Formula: C₈H₈O₅S
• Molecular Weight: 216.21112
• Mol File: 128612-45-3.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 364.6±42.0 °C(Predicted)
• Appearance: /
• Density: 1.484±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1,3-benzodioxol-5-yl methanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-benzodioxol-5-yl methanesulfonate(128612-45-3)
• EPA Substance Registry System: 1,3-benzodioxol-5-yl methanesulfonate(128612-45-3)

Safety Data

• Hazardous Substances Data: 128612-45-3(Hazardous Substances Data)

Upstream product

• 533-31-3 Sesamol 
• 124-63-0 methanesulfonyl chloride 
• 7143-01-3 Methanesulfonic anhydride 

Downstream Products

• 4421-09-4 piperonylonitrile 
• 40804-81-7 2-(benzo[d][1,3]dioxol-5-yl)-1-phenylethan-1-one 
• 4676-39-5 1-(1,3-benzodioxol-5-yl)-2-propanone 
• 209981-66-8 (benzo[d][1,3]dioxol-5-yl)diphenylphosphine oxide 
• 3315-20-6 2-(3',4'-Methylendioxyphenyl)benzoxazol 
• 35493-08-4 N-(benzo[d][1,3]dioxol-5-yl)-2-methylbenzamide 
• 1099595-82-0 4-trifluoromethyl-1-(3,4-methylenedioxyphenyl)lbenzene 
• 24382-05-6 3,4-methylenedioxybiphenyl 
• 440370-62-7 (1S,3S)-1-[3,4-(methylenedioxy)phenoxy]-8-N-methyl-3-p-tolyl-8-aza-bicyclo[3.2.2]nonane 

Relevant articles and documents

Palladium-catalyzed intra-and intermolecular C-H arylation using mesylates: Synthetic scope and mechanistic studies

This paper describes the development of Pd-catalyzed inter-and intramolecular direct arylation using mesylates. Furthermore, a sequential mesylation/arylation protocol using phenols as substrates is described. These transformations are general with respect to the electronics of the C-H substrates and allow for the synthesis of diverse heterocyclic motifs in good yields. Both arenes and heteroarenes efficiently participate in these reactions. Preliminary mechanistic studies are presented for both inter-and intramolecular arylations.

Nickel-catalyzed C-P coupling of aryl mesylates and tosylates with H(O)PR1R2

A method was developed for the nickel-catalyzed phosphonylation of aryl mesylates and tosylates with H(O)PR1R2. To the best of our knowledge, this is the first example of nickel-catalyzed C-P coupling of aryl mesylates and tosylates. Most of the substrates gave moderate to good yields under our catalytic system.

A general palladium catalyst system for suzuki-miyaura coupling of potassium aryltrifluoroborates and aryl mesylates

(Figure presented) The first general examples of palladium-catalyzed Suzuki-type cross-coupling of aryl and heteroaryl mesylates with potassium aryl and heteroaryltrifluoroborates are presented. In addition to biaryl couplings, the cross-coupling reactions of aryl mesylates with alkyl and vinyltrifluoroborate salts have also been successfully accomplished.