1286209-82-2Relevant academic research and scientific papers
A general access to zaragozic acids: Total synthesis and structure elucidation of zaragozic acidD and formal syntheses of zaragozic acidsA and C
Wang, Yuzhou,Metz, Peter
, p. 3335 - 3337 (2011)
One for all: The 2,8-dioxabicyclo[3.2.1]octane derivative 1 served as a general building block for the bioactive title compounds (see scheme; Bz=benzoyl, Bn=benzyl). Two chemoselective alkynylations and two ruthenium-catalyzed hydrogenations had key roles in the first total synthesis of zaragozic acidD, a potent ras-farnesyl protein transferase inhibitor. Copyright
