128991-70-8

Upstream product

• 1202391-84-1 tert-butyl 2-(4-fluorophenyl)hydrazine-1-carboxylate 
• 104-88-1 4-chlorobenzaldehyde 
• 1262991-68-3 tert-butyl 2-(4-fluorophenyl)diazene-1-carboxylate 
• 84713-70-2 N-(4-chlorophenyl)methyleneglycine ethyl ester 
• 371-40-4 4-fluoroaniline 
• 66053-11-0 ethyl 2-(2-(4-fluorophenyl)hydrazono)-3-oxobutanoate 
• 129006-95-7 C₁₀H₁₂FN₃O₂ 
• 122-01-0 4-chloro-benzoyl chloride 

Downstream Products

• 128991-74-2 5-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-1H-[1,2,4]triazole-3-carboxylic acid 

Relevant academic research and scientific papers

Cycloaddition reactions of glycine imine anions to phenylazocarboxylic esters - A new access to 1,3,5-trisubstituted 1,2,4-triazoles

Phenylazocarboxylic tert-butyl esters have recently been shown to be highly versatile building blocks due to their ability to undergo nucleophilic aromatic substitutions under mild conditions, particularly well with [18F]fluoride, and to act as precursors for aryl radicals. In this article, we now report first examples for cycloaddition reactions to phenylazocarboxylates. In a one-pot reaction with readily accessible glycine imines, a variety of highly substituted 1,2,4-triazoles could be obtained.