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129012-04-0

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129012-04-0 Usage

Description

6-BROMOPYRIDINE-2,3-DIAMINE is a chemical compound derived from pyridine, a heterocyclic aromatic compound, featuring a bromine atom and two amine groups. It is utilized in various chemical syntheses and has potential applications in pharmaceuticals, dyes, and specialty chemicals, as well as in material science for developing novel polymeric materials and coatings.

Uses

Used in Pharmaceutical Industry:
6-BROMOPYRIDINE-2,3-DIAMINE is used as a key intermediate in the synthesis of new drugs, contributing to the development of innovative pharmaceuticals for various therapeutic applications.
Used in Dye Industry:
6-BROMOPYRIDINE-2,3-DIAMINE is used as a building block in the production of colorants, enabling the creation of a wide range of dyes with diverse properties and applications.
Used in Specialty Chemicals:
6-BROMOPYRIDINE-2,3-DIAMINE is used as a precursor in the synthesis of various specialty chemicals, enhancing the performance and functionality of these compounds in different industries.
Used in Material Science:
6-BROMOPYRIDINE-2,3-DIAMINE is used in the development of novel polymeric materials and coatings, improving their properties and expanding their applications in various fields.
Used in Chemical Research:
6-BROMOPYRIDINE-2,3-DIAMINE is used as a subject of study for its potential biological and environmental effects, as well as its role in various chemical reactions and processes, contributing to the advancement of scientific knowledge in these areas.

Check Digit Verification of cas no

The CAS Registry Mumber 129012-04-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,0,1 and 2 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 129012-04:
(8*1)+(7*2)+(6*9)+(5*0)+(4*1)+(3*2)+(2*0)+(1*4)=90
90 % 10 = 0
So 129012-04-0 is a valid CAS Registry Number.
InChI:InChI=1/C5H6BrN3/c6-4-2-1-3(7)5(8)9-4/h1-2H,7H2,(H2,8,9)

129012-04-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-Bromopyridine-2,3-diamine

1.2 Other means of identification

Product number -
Other names 6-bromopyridine-2,3-diamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:129012-04-0 SDS

129012-04-0Relevant articles and documents

Synthesis, biological properties and structural study of new halogenated azolo[4,5-b]pyridines as inhibitors of CK2 kinase

Chojnacki,Lindenblatt,Wińska,Wielechowska,Toelzer,Niefind,Bretner

, (2020/12/21)

The new halogenated 1H-triazolo[4,5-b]pyridines and 1H-imidazo[4,5-b]pyridines were synthesised as analogues of known CK2 inhibitors: 4,5,6,7-tetrabromo-1H-benzotriazole (TBBt) and 4,5,6,7-tetrabromo-1H-benzimidazole (TBBi). Their influence on the activity of recombinant human CK2α, CK2α’ and PIM1 kinases was determined. The most active inhibitors were di- and trihalogenated 1H-triazolo[4,5-b]pyridines (4a, 5a and 10a) with IC50 values 2.56, 3.82 and 3.26 μM respectively for CK2α. Furthermore, effect on viability of cancer cell lines MCF-7 (human breast adenocarcinoma) and CCRF-CEM (T lymphoblast leukemia) of all final compounds was evaluated. Finally, three crystal structures of complexes of CK2α1-335 with inhibitors 4a, 5a and 10a were obtained. In addition, new protocol was used to obtain high-resolution crystal structures of CK2α’Cys336Ser in complex with four inhibitors (4a, 5a, 5b, 10a).

NOVEL HETEROCYCLIC DERIVATIVES AND THEIR USES

-

, (2014/10/29)

The present invention relates to novel heterocyclic compounds useful in preparing drugs for treatment of diseases associated with various functions of the histamine 4 receptor. Especially, the said drugs are useful for treatment of inflammatory diseases, allergy, pain, nasal polyps, rhinitis, chronic sinusitis, nasal congestion, nasal itch, asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, atopic dermatitis, psoriasis, eczema, pruritus, itchy skin, urticaria, idiopathic chronic urticaria, scleroderma, conjunctivitis, keratoconjunctivitis, ocular inflammation, dry eye, cardiac dysfunction, arrhythmia, atherosclerosis, multiple sclerosis, inflammatory bowel disease (including colitis, Crohn's disease, ulcerative colitis), inflammatory pain, neuropathic pain, osteoarthritic pain, autoimmune thyroid disease, immune-mediated (also known as type I) diabetes, lupus, post-operative adhesions, vestibular disorders and cancer.

NOVEL COMPOUNDS AS ANTAGONISTS OR INVERSE AGONISTS FOR OPIOID RECEPTORS

-

Page/Page column 91, (2010/09/07)

This invention relates to novel compounds which are antagonists or inverse agonists at one or more of the opioid receptors, to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy.

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