129098-56-2 Usage
Description
(R)-2-((4-BROMOPHENOXY)METHYL)OXIRANE, also known as (R)-2-(4-bromophenoxy)methyloxirane, is an organic compound with the molecular formula C9H9BrO2. It is a chiral epoxide derivative containing a bromophenyl group. (R)-2-((4-BROMOPHENOXY)METHYL)OXIRANE has been studied for its potential applications in organic synthesis and pharmaceutical research. It is crucial to handle and store this compound according to proper safety protocols to prevent any adverse effects on human health and the environment.
Uses
Used in Organic Synthesis:
(R)-2-((4-BROMOPHENOXY)METHYL)OXIRANE is used as a key intermediate in the synthesis of various organic compounds. Its unique structure, which includes a bromophenyl group and an epoxide ring, allows for a wide range of reactions and functional group transformations, making it a valuable building block in the development of new molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (R)-2-((4-BROMOPHENOXY)METHYL)OXIRANE is used as a starting material for the development of new drugs. Its chiral nature and reactive functional groups make it an attractive candidate for the creation of novel therapeutic agents. Researchers are exploring its potential in the design and synthesis of molecules with specific biological activities, such as those targeting various diseases or conditions.
Used in Chemical Research:
(R)-2-((4-BROMOPHENOXY)METHYL)OXIRANE is also utilized in chemical research to study the reactivity and properties of epoxides and bromophenyl groups. (R)-2-((4-BROMOPHENOXY)METHYL)OXIRANE serves as a model system for understanding the fundamental chemical reactions and mechanisms that occur in the presence of these functional groups, which can be applied to the development of new synthetic methods and strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 129098-56-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,0,9 and 8 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 129098-56:
(8*1)+(7*2)+(6*9)+(5*0)+(4*9)+(3*8)+(2*5)+(1*6)=152
152 % 10 = 2
So 129098-56-2 is a valid CAS Registry Number.
129098-56-2Relevant articles and documents
Chiral Macrocyclic Organocatalysts for Kinetic Resolution of Disubstituted Epoxides with Carbon Dioxide
Ema, Tadashi,Yokoyama, Maki,Watanabe, Sagiri,Sasaki, Sota,Ota, Hiromi,Takaishi, Kazuto
supporting information, p. 4070 - 4073 (2017/08/15)
Among chiral macrocycles 1 synthesized, 1m with the 3,5-bis(trifluoromethyl)phenylethynyl group was the best organocatalyst for the enantioselective synthesis of cyclic carbonates from disubstituted or monosubstituted epoxides and CO2. The X-ray crystal structure of 1m revealed a well-defined chiral cavity with multiple hydrogen-bonding sites that is suitable for the enantioselective activation of epoxides. A catalytic cycle proposed was supported by DFT calculations.
PHENYL-(AZA)CYCLOALKYL CARBOXYLIC ACID GPR120 MODULATORS
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Paragraph 00217, (2016/04/20)
The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR120 G protein-coupled receptor modulators which may be used as medicaments.
Enantioselective incorporation of carbon dioxide into epoxides catalyzed by optically active cobalt(II) complexes
Yamada, Wataru,Kitaichi, Yasunori,Tanaka, Hirotaka,Kojima, Tomohide,Sato, Mitsuo,Ikeno, Taketo,Yamada, Tohru
experimental part, p. 1391 - 1401 (2009/06/20)
The enantioselective chemical fixation of CO2 into an epoxide was developed using an optically active ketoimi-natocobalt(II) complex as a chiral Lewis acid. In the presence of a catalytic amount of the cobalt complex and amine base, enantioselective CO2 fixation with an epoxide proceeded with kinetic resolution to afford the corresponding carbonate along with unreacted epoxide, both of which were optically active. To improve their enantioselectivities, the ligand structures of the cobalt complexes and amine bases were examined. Thus, the optimized catalytic system was successfully applied to various epoxides to obtain the corresponding optically active cyclic carbonates and to recover epoxides with good-to-high enantioselectivities.
