129121-95-5

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 98-86-2 acetophenone 
• 129122-52-7 (S)-3-(tert-Butyl-diphenyl-silanyloxy)-4-({(E)-2-[4-(4-fluoro-phenyl)-2-isopropyl-6-phenyl-pyridin-3-yl]-vinyl}-methoxy-phosphinoyl)-butyric acid methyl ester 
• 122253-00-3 4-(4-fluorophenyl)-2-(1-methylethyl)-6-phenyl-3-pyridinemethanol 
• 1608-51-1 4-fluorochalcone 
• 129122-57-2 (S)-4-({(E)-2-[4-(4-Fluoro-phenyl)-2-isopropyl-6-phenyl-pyridin-3-yl]-vinyl}-methoxy-phosphinoyl)-3-hydroxy-butyric acid methyl ester 
• 129122-41-4 1,1-Dibromo-2-(4-(4-fluorophenyl)-2-(1-methylethyl)-6-phenylpyridin-3-yl)ethene 
• 129122-42-5 3-ethynyl-4-(4-fluorophenyl)-2-(1-methylethyl)-6-phenylpyridine 
• 129122-55-0 (E)-4-(4-Fluorophenyl)-3-(2-iodoethenyl)-2-(1-methylethyl)-6-phenylpyridin 
• 128108-47-4 4-(4-fluorophenyl)-2-(1-methylethyl)-6-phenyl-3-pyridinecarboxaldehyde 
• 122252-56-6 β-(4-fluorophenyl)-α-(2-methyl-1-oxopropyl)-δ-oxobenzenepentanoic acid, ethyl ester 
• 122252-70-4 4-(4-fluorophenyl)-2-(1-methylethyl)-6-phenyl-3-pyridinecarboxylic acid, ethyl ester 

Relevant academic research and scientific papers

PYRIDINE ANCHORS FOR HMG-COA REDUCTASE INHIBITORS

Compounds which are useful as inhibitors of cholesterol biosynthesis and thus as hypocholesterolemic agents are provided which have a quinoline or a pyridine anchor attached by means of a linker to a binding domain sidechain, which compounds inhibit the e

Phosphorus-Containing Inhibitors of HMG-CoA Reductase. 2. Synthesis and Biological Activites of a Series of Substituted Pyrydynes Containing a Hydroxyphosphinyl Moiety

A series of 2,3,4,(5),6-substituted pyridines containing a hydroxyphosphinyl functionality have been prepared and were evaluated for their ability to inhibit the enzyme HMG-CoA reductase.Systematic substitution of both R1-R4 and X-Y