1292307-06-2

Basic information

• Product Name: (1S,3R)-methyl 3-hydroxycyclopentanecarboxylate
• Synonyms: methyl (1S,3R)-3-hydroxycyclopentanecarboxylate;(1S,3R)-3-Hydroxycyclopentane carboxylic acid methyl ester
• CAS NO: 1292307-06-2
• Molecular Formula: C7H12O3
• Molecular Weight: 144.17
• Mol File: 1292307-06-2.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: (1S,3R)-methyl 3-hydroxycyclopentanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,3R)-methyl 3-hydroxycyclopentanecarboxylate(1292307-06-2)
• EPA Substance Registry System: (1S,3R)-methyl 3-hydroxycyclopentanecarboxylate(1292307-06-2)

Safety Data

• Hazardous Substances Data: 1292307-06-2(Hazardous Substances Data)

Usage

Description

(1S,3R)-3-Hydroxycyclopentane carboxylic acid methyl ester is a synthetic intermediate useful for pharmaceutical synthesis.

Upstream product

• 58101-60-3 methyl cyclopent-3-ene-1-carboxylate 
• 98-78-2 3-Oxo-cyclopentanecarboxylic acid 
• 132076-27-8 (R)-methyl 3-oxocyclopentanecarboxylate 
• 13012-38-9 (1R)-3-oxocyclopentane-1-carboxylic acid 
• 67-56-1 methanol 
• 32811-75-9 methyl 3-oxocyclopentane-1-carboxylate 
• 86885-57-6 rac-methyl (1R,5S)-6-oxabicyclo[3.1.0]hexane-3-carboxylate 

Downstream Products

• 109646-10-8 (+/-)-cis-3-methoxy-cyclopentanecarboxylic acid p-toluidide 

Relevant articles and documents

Horse Liver Alcohol Dehydrogenase-catalyzed Enantioselective Reduction of Cyclic Ketones: The Effect of the Hydrophobic Side Chain of the Substrate on the Stereoselectivity of the Reaction

Horse liver alcohol dehydrogenase (HLADH)-catalyzed enantioselective reductions of alkyl 3-oxocyclopentanecarboxylates, endo-5-acyloxybicycloheptan-2-ones and exo-5-acyloxybicycloheptan-2-ones gave the corresponding homochiral alcohols and ketones and the interaction between the hydrophobic side chain of the substrate and the hydrophobic zone in the active site played an important role in the specificity of the reduction.The stereoselectivities of the reactions were interpreted on the basis of the cubic space section model and a new rule, which contributes to development of a specificity analysis on the basis of the model, is introduced.

INHIBITORS OF RHO/MRTF/SRF-MEDIATED GENE TRANSCRIPTION AND METHODS FOR USE OF THE SAME

Disclosed herein are inhibitors of Rho/MRTF/SRF-mediated gene transcription, and methods for their use in treating or preventing diseases such as cancer and fibrosis. In particular, disclosed herein are compounds of Formula (I) and pharmaceutically accept

N-substituted imidazole carboxylate compounds, and preparation method and medical application thereof

The invention relates to a compound represented as a general formula (I) or a stereoisomer, solvate, pharmaceutically acceptable salt or eutectic crystal of the compound, and a composition, preparation method and medical application of the compound, the stereoisomer, the solvate, the pharmaceutically acceptable salt and the eutectic crystal. The general formula (I) is shown as follows, and the definition of each substituent group is consistent as in the specification.