129299-05-4Relevant articles and documents
Design and synthesis of highly potent fumagillin analogues from homology modeling for a human MetAP-2
Han, Cheol Kyu,Ahn, Soon Kil,Choi, Nam Song,Hong, Ryung Kee,Moon, Seung Kee,Chun, Hyoung Sik,Lee, Sang Joon,Kim, Jung Woo,Hong, Chung Il,Kim, Deukjoon,Yoon, Jeong Hyeok,No, Kyoung Tai
, p. 39 - 43 (2000)
New fumagillin analogues were designed through structure-based molecular modeling with a human methionine aminopeptidase-2. Among the fumagillin analogues, cinnamic acid ester derivative CKD-731 showed 1000-fold more potent proliferation inhibitory activi