129409-68-3

Upstream product

• 116088-83-6 (p-Cyanophenyl)dimethylchlorosilane 
• 1066-35-9 dimethylmonochlorosilane 
• 623-00-7 4-bromobenzenecarbonitrile 
• 3058-39-7 4-iodobenzonitrile 

Downstream Products

• 129409-67-2 tetramethyldiphenyldisiloxane-4,4'-dicarboxaldehyde 
• 1393446-15-5 4-(methoxydimethylsilyl)benzonitrile 
• 767-00-0 4-cyanophenol 
• 18537-19-4 4,4'-(1,1,3,3-tetramethyldisiloxane-1,3-diyl)dibenzonitrile 
• 129409-71-8 C₃₈H₄₈N₂O₃Si₂ 
• 129409-72-9 C₃₈H₄₈N₂OSi₂ 
• 129409-70-7 C₃₂H₃₆N₂O₃Si₂ 
• 129409-69-4 4-[3-(4-Formyl-phenyl)-1,1,3,3-tetramethyl-disiloxanyl]-benzoic acid 
• 18054-10-9 4,4'-(1,1,3,3-tetramethyldisiloxane-1,3-diyl)dibenzoic acid 

Relevant academic research and scientific papers

Rhodium-catalyzed carbonylative synthesis of silyl-substituted indenones

A novel and efficient rhodium-catalyzed procedure for the preparation of silyl-substituted indenones has been developed. Using silanes and internal alkynes as the substrates, in the presence of CO, good to excellent yields of the desired indenones were isolated. A wide range of functional groups, encompassing esters, amines, nitriles and halides, is compatible in this system.

Ru(ii)-Pheox-catalyzed Si-H insertion reaction: construction of enantioenriched carbon and silicon centers

We established a highly enantioselective Si-H insertion reaction to construct chiral centers at the carbon and silicon atoms, using a Ru(ii)-pheox catalyst. The catalytic asymmetric Si-H insertion reaction of α-methyl-α-diazoesters proceeded smoothly with excellent stereoinduction at both the neighboring carbon and silicon atoms (up to 99% yield and 99% ee).

Mechanistic Study of Arylsilane Oxidation through 19F NMR Spectroscopy

The mechanism of the oxidation of arylsilanes to phenols has been investigated using19F NMR spectroscopy. The formation of silanols in these reactions results from a rapid background equilibrium between silanol and alkoxysilane; the relative rates of reaction of these species was evaluated by modeling of concentration profiles obtained through 19F NMR spectroscopic reaction monitoring. Combining these results with a study of initial rates of phenol formation, and of substituent electronic effects, a mechanistic picture involving rapid and reversible formation of a pentavalent peroxide ate complex, prior to rate-limiting aryl migration, has evolved.

Bimetallic Nanoshells as Platforms for Metallo- and Biometallo-Catalytic Applications

The use of gold, silver, platinum and palladium for preparation of bimetallic nanoshells (AgAu, AgPt, and AgPdNSs, respectively) and their use for metallo- and bio-metallo catalytic applications have been described. Bimetallic nanoshells (metallo-catalysts) were employed for silane oxidation to silanols and hydrogen (H2) production. Fast and efficient oxidation of several silanes was observed after only 1 h at room temperature, by employing AgPd NSs as catalyst, acetone as solvent, and water as oxidant. Interestingly, bio-metallo-catalysts (NSs-CALB) prepared from lipase attachment to the bimetallic nanoshells, displayed promising bi-catalytic activities (enzymatic: transesterification; metallic: silane oxidation).

Synthesis of phenols via fluoride-free oxidation of arylsilanes and arylmethoxysilanes

Rapid, efficient methods have been developed to prepare phenols from the oxidation of arylhydrosilanes. The effects of arene substituents and fluoride promoters on this process show that while electron-deficient arenes can undergo direct oxidation from the hydrosilane, electron-rich aromatics benefit from silane activation via oxidation to the methoxysilane using homogeneous or heterogeneous transition metal catalysis. The combination of these two oxidations into a streamlined flow procedure involving minimal processing of reaction intermediates is also reported.

Synthesis of Silicon Containing Benzaldehydes and Conversion to Schiff's Bases

Synthesis of the first silicon substituted benzaldehyde derivatives is described.Reduction of tetramethyldiphenyldisiloxane-4,4'-dicarboxylic acid chloride with tri-t-butoxylithiumaluminium hydride gives tetramethyldiphenyldisiloxane-4,4'-dicarboxaldehyde in 40percent yield.Synthesis and characterization of Schiff's base derivatives are described.