129687-45-2Relevant academic research and scientific papers
Iron-Catalyzed Direct Diazidation for a Broad Range of Olefins
Yuan, Yong-An,Lu, Deng-Fu,Chen, Yun-Rong,Xu, Hao
, p. 534 - 538 (2016/02/27)
Reported herein is a new iron-catalyzed diastereoselective olefin diazidation reaction which occurs at room temperature (1-5 mol % of catalysts and d.r. values of up to >20:1). This method tolerates a broad range of both unfunctionalized and highly functionalized olefins, including those that are incompatible with existing methods. It also provides a convenient approach to vicinal primary diamines as well as other synthetically valuable nitrogen-containing building blocks which are difficult to obtain with alternative methods. Preliminary mechanistic studies suggest that the reaction may proceed through a new mechanistic pathway in which both Lewis acid activation and iron-enabled redox-catalysis are crucial for selective azido-group transfer. With iron hand: The title reaction proceeds at room temperature and tolerates a broad range of both unfunctionalized and highly functionalized olefins. It also provides a convenient synthetic approach to a variety of nitrogen-containing building blocks. Preliminary mechanistic studies suggest both Lewis acid activation and iron-enabled redox catalysis are crucial for the selective azido-group transfer.
An Expedient Synthesis of Vicinal Diamines from Alkenes and Cycloalkenes
Osowska-Pacewicka, Krystyna,Zwierzak, Andrzej
, p. 505 - 508 (2007/10/02)
A new procedure for the facile preparation of various vicinal diamines is developed that utilizes diethyl N-(β-bromoalkyl)phosphoramidates 2 easily accessible by ionic addition of diethyl N,N-dibromophosphoramidate (DBPA) to alkenes and cycloalkenes 1.Cru
