129779-06-2

Basic information

• Product Name: (S)-2-((S)-2-Cyclopentylsulfanylmethyl-3-phenyl-propionylamino)-hexanoic acid tert-butyl ester
• CAS NO: 129779-06-2
• Molecular Weight: 433.656
• Mol File: 129779-06-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-((S)-2-Cyclopentylsulfanylmethyl-3-phenyl-propionylamino)-hexanoic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-((S)-2-Cyclopentylsulfanylmethyl-3-phenyl-propionylamino)-hexanoic acid tert-butyl ester(129779-06-2)
• EPA Substance Registry System: (S)-2-((S)-2-Cyclopentylsulfanylmethyl-3-phenyl-propionylamino)-hexanoic acid tert-butyl ester(129779-06-2)

Safety Data

• Hazardous Substances Data: 129779-06-2(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 123878-44-4 L-N-<(2R)-2-benzyl-3-hydroxypropionyl>norleucine t-butyl ester 
• 123802-54-0 L-N-[(2RS)-2-ethoxycarbonyl-3-phenylpropionyl]norleucine tert-butyl ester 
• 123802-80-2 (R)-2-hydroxymethyl-3-phenylpropionic acid 
• 15911-73-6 L-norleucine tert-butyl ester 
• 2985-39-9 2-benzylmalonic acid monoethyl ester 
• 1679-07-8 cyclopentylthiol 
• 123803-52-1 L-N-[(2R)-2-benzyl-3-(p-toluenesulfonyloxy)propionyl]norleucine tert-butyl ester 

Downstream Products

• 129831-74-9 (S)-2-((S)-2-Benzyl-3-cyclopentanesulfonyl-propionylamino)-hexanoic acid tert-butyl ester 
• 129779-07-3 (4S,5S)-5-[(S)-2-((S)-2-Benzyl-3-cyclopentanesulfonyl-propionylamino)-hexanoylamino]-2-ethyl-4-hydroxy-7-methyl-octanoic acid isobutyl-amide 

Relevant articles and documents

Synthesis of Renin Inhibitors Containing a Sulfonemethylene Isostere at Their N-Terminals

We describe an efficient synthesis of highly active renin inhibitors containing a sulfonemethylene isostere at their N-terminals and a hydroxyethylene isosters at their C-terminals.The stereospecific synthesis of N-terminal key intermediate, L-N-norleucine t-butyl ester is described.