129886-15-3

Upstream product

• 96149-40-5 Benzoic acid (2S,3S,4R)-5,5-bis-benzylsulfanyl-2,3,4-trihydroxy-pentyl ester 
• 98-88-4 benzoyl chloride 
• 124-63-0 methanesulfonyl chloride 
• 404574-13-6 2,3,5-tri-O-benzoyl-L-arabinose dibenzyl dithioacetal 
• 404574-12-5 methyl 2,3,5-tri-O-benzoyl-1-α-L-arabinofuranoside 
• 100-53-8 phenylmethanethiol 

Downstream Products

• 404574-14-7 C₃₃H₂₈O₆S₂ 
• 129905-16-4 C₃₀H₂₄N₂O₈S 
• 129886-18-6 C₂₈H₂₄O₈S 

Relevant academic research and scientific papers

Synthesis of four ester protected thiofuranose sugars

The products obtained by titanium tetrachloride mediated dithioacetalization of four pentofuranoside derivatives were converted to thiofuranose sugars, either by direct cyclization via the unstable trifiate intermediate, or by treatment of the derived mesylate. A facile inversion of a D-ribose dibenzyl dithioacetal 9 to an L-lyxose dibenzyl dithioacetal 12 via hydrolysis of the Mitsunobu derived formate intermediate is also described.

RESOLUTION AND DETERMINATION OF ENANTIOMERIC EXCESSES OF CHIRAL ALDEHYDES VIA CHIRAL IMIDAZOLIDINES

Enantiomeric purity of chiral aldehydes was determined by NMR analysis of derived imidazolidines.The diastereomeric imidazolidines were easily separated by silica gel column and converted into enantiomerically pure aldehyde by acid hydrolysis.