404574-12-5Relevant academic research and scientific papers
Enzymatic synthesis of alkyl arabinofuranosides using a thermostable α-L-arabinofuranosidase
Rémond, Caroline,Ferchichi, Mounir,Aubry, Nathalie,Plantier-Royon, Richard,Portella, Charles,O'Donohue, Michael J.
, p. 9653 - 9655 (2002)
A thermostable α-L-arabinofuranosidase was tested for its ability to perform transglycosylation with different alcohol acceptors. Reactions were characterized by high rates with optimal synthesis being obtained within 10 min. Both primary and secondary al
MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF
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Page/Page column 77-79; 82; 84; 146-148, (2021/02/19)
The present disclosure provides oligomeric compounds comprising a modified oligonucleotide having at least one stereo-non-standard nucleoside. An oligomeric compound comprising a modified oligonucleotide consisting of 12-30 linked nucleosides, wherein at least one nucleoside of the modified oligonucleotide is a stereo-non-standard nucleoside; and wherein the oligomeric compound is selected from among an RNAi compound, a modified CRISPR compound, and an artificial mRNA compound.
MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF
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Page/Page column 71-72, (2020/05/15)
The present disclosure provides oligomeric compounds comprising a modified oligonucleotide having at least one stereo-non-standard nucleoside.
Discovery of Glycosylated Genipin Derivatives as Novel Antiviral, Insecticidal, and Fungicidal Agents
Xia, Qing,Dong, Jianyang,Li, Ling,Wang, Qiang,Liu, Yuxiu,Wang, Qingmin
, p. 1341 - 1348 (2018/02/19)
A series of novel genipin glycoside derivatives incorporating 11 glycosidic moieties at either the 1 or 10 position of genipin were designed and synthesized. These compounds exhibited moderate to excellent inhibitory activities against tobacco mosaic virus. Especially, the in vitro and in vivo activities of compounds 6e, 7c, 7d, 7f, 7h, and 7i were comparable to that of ribavirin. In particular, compound 7c, the mannosyl derivative of genipin at the 10 position, showed the best activity. The series of genipin glycosyl derivatives also displayed fungicidal activities against 14 kinds of phytopathogenic fungi, especially for Rhizoctonia cerealis and Sclerotinia sclerotiorum. Moreover, compound 6h exhibited good insecticidal activity against diamondback moth; compounds 7b, 7c, and 7g exhibited moderate insecticidal activity against three kinds of Lepidoptera pests (oriental armyworm, cotton bollworm, and corn borer); and compound 7e showed excellent larvacidal activities against mosquito.
