129932-29-2

Basic information

• Product Name: Phosphine oxide, (difluoromethyl)diphenyl-
• CAS NO: 129932-29-2
• Molecular Formula: C13H11F2OP
• Molecular Weight: 252.2
• Mol File: 129932-29-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Phosphine oxide, (difluoromethyl)diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphine oxide, (difluoromethyl)diphenyl-(129932-29-2)
• EPA Substance Registry System: Phosphine oxide, (difluoromethyl)diphenyl-(129932-29-2)

Safety Data

• Hazardous Substances Data: 129932-29-2(Hazardous Substances Data)

Upstream product

• 75-45-6 Chlorodifluoromethane 
• 4559-70-0 Diphenylphosphine oxide 
• 81290-20-2 (trifluoromethyl)trimethylsilane 

Downstream Products

• 131581-42-5 2-(2,2-Difluoro-1-methyl-vinyl)-1,4-dimethoxy-benzene 
• 700-59-4 β,β-difluoro-α-methylstyrene 
• 512779-34-9 Diphenyl-phosphinic acid 1-[(3S,8R,9S,10R,13S,14S)-3-(tert-butyl-dimethyl-silanyloxy)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2,2-difluoro-1-methyl-ethyl ester 
• 131581-41-4 1,1-difluoro-2-(3,4-dimethoxyphenyl)ethene 
• 569-72-2 1,1-difluoro-2,2-diphenylethylene 
• 145-13-1 Pregnenolone 

Relevant articles and documents

Siladifluoromethylation and Deoxo-trifluoromethylation of PV-H Compounds with TMSCF3: Route to PV-CF2- Transfer Reagents and P-CF3 Compounds

A method for siladifluoromethylation of dialkyl phosphonates and secondary phosphine oxides with TMSCF3 to produce nucleophilic PV-CF2- transfer reagents is disclosed, with multigram scale reactions included. Condition-dependent divergent reactivity under the established conditions is demonstrated by the formation of trifluoromethylphosphines. Both one-pot transformations are operationally simple and employ inexpensive materials. Mechanistic investigations suggest the divergent reactivity originates from a common intermediate, with Li+ concentration directing the chemoselectivity.

2-'-ethenylidene cytidine, uridine and guanosine derivatives

This invention relates to certain novel 2'-halomethylidene, 2'-ethenylidene and 2'-ethynyl cytidine, uridine and guanosine derivatives, and compositions thereof, which are useful in the treatment of patients afflicted with neoplastic or viral disease stat

DI- AND TETRA-FLUORO ANALOGS OF SQUALENE AS INHIBITORS OF SQUALENE EPOXIDASE

This invention relates to certain novel di- and tetra-fluoro analogs of squalene and to their methods of use in lowering plasma cholesterol and in inhibiting squalene epoxidase in patients in need thereof.