130232-98-3

Basic information

• Product Name: (R)-t-Butyl glycidyl ether
• Synonyms: (R)-t-Butyl glycidyl ether;(2R)-2-[(1,1-dimethylethoxy)methyl]Oxirane;(2R)-2-(tert-Butoxymethyl)oxirane
• CAS NO: 130232-98-3
• Molecular Formula: C₇H₁₄O₂
• Molecular Weight: 130.18486
• Mol File: 130232-98-3.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-t-Butyl glycidyl ether(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-t-Butyl glycidyl ether(130232-98-3)
• EPA Substance Registry System: (R)-t-Butyl glycidyl ether(130232-98-3)

Safety Data

• Hazardous Substances Data: 130232-98-3(Hazardous Substances Data)

Usage

General Description

(R)-t-Butyl glycidyl ether is a chemical compound with the molecular formula C7H14O2. It is a colorless liquid with a faint odor, and is commonly used as a reactive diluent in epoxy resin formulations. (R)-t-Butyl glycidyl ether is also used in the synthesis of other organic compounds, and as a starting material for the production of various polymers. It is considered to be a low hazard chemical, with a low potential for acute toxicity. However, prolonged or repeated exposure to this compound may cause irritation to the skin, eyes, and respiratory system. Additionally, it is important to handle (R)-t-Butyl glycidyl ether with caution and in accordance with proper safety procedures to prevent any potential health risks.

Upstream product

• 7665-72-7 t-butyl glycidyl ether 
• 67843-74-7 (S)-epichlorohydrin 
• 75-65-0 tert-butyl alcohol 

Downstream Products

• 97798-48-6 (S)-(2,3-dihydroxypropyl) phenyl sulfide 

Relevant articles and documents

Enantioselective Resolution Copolymerization of Racemic Epoxides and Anhydrides: Efficient Approach for Stereoregular Polyesters and Chiral Epoxides

Herein we report an efficient strategy for preparing isotactic polyesters and chiral epoxides via enantioselective resolution copolymerization of racemic terminal epoxides with anhydrides, mediated by enantiopure bimetallic complexes in conjunction with a nucleophilic cocatalyst. The chirality of both the axial linker and the diamine backbones of the ligand are responsible for the chiral induction of this kinetic resolution copolymerization process. The catalyst systems exhibit exceptional levels of enantioselectivity with a kinetic resolution coefficient exceeding 300 for various racemic epoxides, affording highly isotactic copolymers (selectivity factors of more than 300) with a completely alternating structure and low polydispersity index. Most of the produced isotactic polyesters are typical semicrystalline materials with melting temperatures in the range from 77 to 160 °C.

A new dinuclear chiral salen complexes for asymmetric ring opening and closing reactions: Synthesis of valuable chiral intermediates

A new dinuclear chiral Co(salen) complexes bearing group 13 metals have been synthesized and characterized. The easily prepared complexes exhibited very high catalytic reactivity and enantioselectivity for the asymmetric ring opening of epoxides with H2O, chloride ions and carboxylic acids and consequently provide enantiomerically enriched terminal epoxides (>99% ee). It also catalyzes the asymmetric cyclization of ring opened product, to prepare optically pure terminal epoxides in one step. The homogeneous dinuclear chiral Co(salen) have been covalently immobilized on MCM-41. The potential benefits of heterogenization include facilitation of catalyst separation and recyclability requiring very simple techniques. The system described is very efficient.

The efficient resolution of protected diols and hydroxy aldehydes by lipases: Steric auxilliary approach and synthetic applications

1,n-Diols (n = 2-5) and 2-hydroxy aldehydes protected with a steric auxilliary are transformed by Pseudomonas lipases with high enantioselectivity, thus allowing the efficient resolution of these molecules and the synthesis of related derivatives with high optical purity.