130339-76-3Relevant academic research and scientific papers
Functionalization of pyridyl ketones using deprotolithiation-: In situ zincation
Hedidi, Madani,Erb, William,Lassagne, Frédéric,Halauko, Yury S.,Ivashkevich, Oleg A.,Matulis, Vadim E.,Roisnel, Thierry,Bentabed-Ababsa, Ghenia,Mongin, Florence
, p. 63185 - 63189 (2016)
The metallation of aryl ketones was achieved by using LiTMP in the presence of ZnCl2·TMEDA, as evidenced by subsequent interception with iodine or by a palladium-catalysed cross-coupling reaction. One of the synthesized iodo ketones has been further elaborated to reach derivatives of biological interest.
Efficient synthesis of functionalized organozinc compounds by the direct insertion of zinc into organic iodides and bromides
Krasovskiy, Arkady,Malakhov, Vladimir,Gavryushin, Andrei,Knochel, Paul
, p. 6040 - 6044 (2007/10/03)
(Chemical Equation Presented) Insider dealing: A wide range of poly-functional (hetero)aromatic and aliphatic zinc reagents can be easily prepared in THF. The compounds are formed by a Zn insertion reaction mediated by the addition of LiCl (see scheme; All = allyl).
