130447-21-1

Basic information

• Product Name: Zinc, (4-bromophenyl)chloro-
• CAS NO: 130447-21-1
• Molecular Formula: C6H4BrClZn
• Molecular Weight: 256.845
• Mol File: 130447-21-1.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Zinc, (4-bromophenyl)chloro-(CAS DataBase Reference)
• NIST Chemistry Reference: Zinc, (4-bromophenyl)chloro-(130447-21-1)
• EPA Substance Registry System: Zinc, (4-bromophenyl)chloro-(130447-21-1)

Safety Data

• Hazardous Substances Data: 130447-21-1(Hazardous Substances Data)

Upstream product

• 18620-02-5 (4-bromophenyl)magnesium bromide 
• 7646-85-7 zinc(II) chloride 
• 106-37-6 1.4-dibromobenzene 
• 1205517-05-0 C₆H₄Cl₃In 

Downstream Products

• 92-86-4 4-(4-bromophenyl)bromobenzene 
• 14310-24-8 1-bromo-4-(2-phenylethyl)benzene 
• 2051-99-2 1-bromo-4-isobutylbenzene 
• 4762-31-6 4-Bromphenylphosphindichlorid 
• 1205517-14-1 1-bromo-4-(2-methylheptyl)benzene 
• 51554-93-9 1-bromo-4-octylbenzene 
• 130447-14-2 4'''-Dimethylamino-[1,4';1',1'';4'',1''']quaterphenyl-4-carbonitrile 
• 189093-23-0 1,8-Bis-(4-vinyl-phenyl)-naphthalene 
• 7702-38-7 N-(4-bromophenyl)benzamide 
• 109287-42-5 4-bromophenyl 4-methylphenyl selenide 
• 106-40-1 4-bromo-aniline 
• 129921-03-5 (E)-1-(4-bromophenyl)-1-<4-(2-chloroethoxy)phenyl>-2-phenyl-1-butene 
• 129921-03-5 (Z)-1-(4-bromophenyl)-1-<4-(2-chloroethoxy)phenyl>-2-phenyl-1-butene 

Relevant articles and documents

Quantitative kinetic investigation on transmetalation of ArZnX in a Pd-catalysed oxidative coupling

Transmetalation is the rate-limiting step. [R-Pd-Ar] was suggested to be the resting species from the kinetic studies. Quantitative measurement of the transmetalation of ArZnCl with [R-Pd-Ar] from a live Pd-catalysed oxidative coupling reaction was conducted and the corresponding activation enthalpy was determined as 12.3 kcal mol-1. The Royal Society of Chemistry 2013.

The Formation of P-C Bonds Utilizing Organozinc Reagents for the Synthesis of Aryl- A nd Heteroaryl-Dichlorophosphines

Aryl- A nd heteroaryl-dichlorophosphines are mildly and selectively made in a one-pot synthesis in moderate to good yields starting from the respective aryl bromides or five-membered heterocycles, following lithiation with nBuLi, transmetalation with ZnCl

Rh-Catalyzed Conjugate Addition of Arylzinc Chlorides to Thiochromones: A Highly Enantioselective Pathway for Accessing Chiral Thioflavanones

A highly efficient asymmetric synthesis of chiral thioflavanones is developed via conjugate addition of arylzinc reagents to thiochromones using Rh(COD)Cl2/(R)-3,4,5-MeO-MeOBIPHEP catalyst. This method overcomes catalyst poisoning and substrate inertness and affords a series of chiral thioflavanones (2-arylthiochroman-4-ones) in good yields (up to 91% yield) with excellent ee values (up to 97% ee). The established asymmetric synthesis paves the way for further pharmaceutical studies.