2051-99-2

Usage

Uses

Used in Pharmaceutical Industry:
1-Bromo-4-isobutylbenzene is used as an intermediate in the synthesis of pharmaceuticals for its ability to facilitate the creation of various medicinal compounds.
Used in Agrochemical Industry:
In the agrochemical sector, 1-Bromo-4-isobutylbenzene serves as an intermediate, contributing to the development of agrochemicals that can enhance crop protection and productivity.
Used in Organic Synthesis:
1-Bromo-4-isobutylbenzene is utilized as a reagent in organic synthesis, playing a crucial role in the formation of a wide range of organic compounds due to its reactivity and functional group compatibility.

InChI:InChI=1/C10H13Br/c1-8(2)7-9-3-5-10(11)6-4-9/h3-6,8H,7H2,1-2H3

Upstream product

• 538-93-2 1-phenyl-2-methylpropane 
• 83558-89-8 2-methyl-3-(4-bromophenyl)-propene 
• 56985-67-2 4-Bromo-α-(1-methylethyl)benzenemethanol 
• 56985-68-3 1-bromo-4-(2-methyl-1-propenyl)benzene 
• 6731-23-3 triisobutylindium 
• 130447-21-1 (4-bromophenyl)zinc(II) chloride 
• 49660-93-7 4'-bromoisobutyrophenone 
• 75-30-9 2-iodo-propane 
• 57477-93-7 hydrazone of p-bromobenzaldehyde 
• 1122-91-4 4-bromo-benzaldehyde 
• 106-37-6 1.4-dibromobenzene 
• 18620-02-5 (4-bromophenyl)magnesium bromide 

Downstream Products

• 19409-00-8 3-(p-Isobutyl-phenyl)-2-hydroxy-propylchlorid 
• 222020-95-3 1-Isobutyl-4-{(R)-2-[(2R,5S)-2-isopropyl-5-methyl-cyclohex-(E)-ylidene]-1-methyl-ethyl}-benzene 
• 57438-46-7 1-(1-methyl-2-propenyl)-4-(2-methylpropyl)benzene 
• 60057-62-7 2-(4-isobutyl-phenyl)-2-hydroxy-propionic acid 
• 180293-49-6 2-fluoro-2-[4-(2-methylpropyl)phenyl]propionic acid 
• 180293-53-2 methyl 2-fluoro-2-[4-(2-methylpropyl)phenyl]propionate 
• 185329-90-2 3-(4-iso-butylphenyl)thiophene-2-sulfonyl chloride 
• 86618-05-5 tert-butyl 2-(4-isobutylphenyl)propanoate 
• 1001010-49-6 5-(4-isobutyl-phenyl)-furan-2-carbaldehyde 
• 1368756-09-5 C₁₄H₁₇N₃O 
• 1033753-01-3 4,4,5,5-tetramethyl-2-[4-(2-methylpropyl)phenyl]-1,3,2-dioxaborolane 

Relevant academic research and scientific papers

Method for preparing para-substituted bromobenzene

The present application relates to a method for preparing para-substituted bromobenzene represented by formula 2, which is characterized in that the method comprises the steps of: in organic solvents,in the presence of alkali, the compound represented by

Nickel-catalyzed cross-coupling of umpolung carbonyls and alkyl halides

An effective nickel-catalyzed cross-coupling of Umpolung carbonyls and alkyl halides was developed. Complementary to classical alkylation techniques, this reaction utilizes Umpolung carbonyls as the environmentally benign alkyl nucleophiles, providing an efficient and selective catalytic alternative to the traditional use of highly reactive alkyl organometallic reagents.

Nickel-Catalyzed Cross-Coupling of Umpolung Carbonyls and Alkyl Halides

An effective nickel-catalyzed cross-coupling of Umpolung carbonyls and alkyl halides was developed. Complementary to classical alkylation techniques, this reaction utilizes Umpolung carbonyls as the environmentally benign alkyl nucleophiles, providing an efficient and selective catalytic alternative to the traditional use of highly reactive alkyl organometallic reagents.

Bromination of aromatic compounds using ammonium bromide and oxone

A simple, efficient and mild method for the selective bromination of activated aromatic compounds using ammonium bromide as the source of bromine and Oxone as the oxidant in methanol or water as solvent is reported. The reaction proceeds at ambient temperature in yields ranging from moderate to excellent without a catalyst. Georg Thieme Verlag Stuttgart.

Highly selective palladium-catalyzed oxidative Csp2-Csp 3 cross-coupling of arylzinc and alkylindium reagents through double transmetallation

Using desyl chloride (2-chloro-1,2-diphenylethanone) as the oxidant, the palladium-catalyzed reaction of arylzinc with alkylindium reagents occurred smoothly in a highly selective manner to afford the products in 57-90% yields. Preliminary kinetic data in

Efficient syntheses of optically active 2-arylalkanoic acids

A highly enantioselective synthesis of 2-axylpropanoic acid was achieved, using a new developed methodology of cuprate addition to chiral carbonates derived from menthone.

Thiophenesulfonamides as endothelin receptor antagonists

The synthesis and in vitro binding affinities of a series of thiophenesulfonamides as ET(A) selective endothelin receptor antagonists is described. The most potent inhibitor displayed an IC50 of 43 nM and 3 μM to ET(A) and ET(B) receptors, respectively.