130483-75-9Relevant academic research and scientific papers
The Addition of Lithium Salts of O-Alkyloximes to Aldehydes: Synthesis of β-Keto O-Alkyloximes
Shatzmiller, Shimon,Bahar, Eliezer,Bercovici, Sorin,Cohen, Alexander,Verdoorn, Gerhard
, p. 502 - 504 (2007/10/02)
Addition of lithium salts of oxime O-ethers to aldehydes affords the thermodynamically unfavored β-hydroxy (Z)-O-alkyloximes.Oxidation of the hydroxy function with chromium trioxide/pyridine complex gives the β-keto O-alkyloximes.Facile alkylation of the 1,3-dicarbonyl analogs is possible via their sodium or lithium salts.
