13061-28-4 Usage
General Description
1-(2,4,5-trichlorophenyl)ethan-1-one, also known as triclocarban, is an antimicrobial compound used in various personal care products such as soaps, detergents, and body washes. It is a white to light yellow crystalline powder that has a chlorinated aromatic structure. Triclocarban has been widely used as an antibacterial agent due to its ability to inhibit the growth of bacteria and fungi. However, there is growing concern about its potential negative impact on human health and the environment, leading to restrictions on its use in some regions. Studies have shown that triclocarban can accumulate in the environment and may have endocrine-disrupting effects. As a result, there is ongoing research into alternative antimicrobial compounds with safer profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 13061-28-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,0,6 and 1 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 13061-28:
(7*1)+(6*3)+(5*0)+(4*6)+(3*1)+(2*2)+(1*8)=64
64 % 10 = 4
So 13061-28-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H5Cl3O/c1-4(12)5-2-7(10)8(11)3-6(5)9/h2-3H,1H3
13061-28-4Relevant articles and documents
Fused thia-heterocycles via isothiocyanates. Part I. Facile synthesis of some new 1-benzothiopyran-4-one derivatives
Barhoumi, Lina M.,El-Abadelah, Mustafa M.,Sabri, Salim S.,Voelter, Wolfgang
, p. 369 - 375 (2017/05/16)
A selected set of new 4H-benzothiopyran-4-one derivatives 6a-h has been prepared by a one-pot reaction involving deprotonated methyl 3-oxo-3(2′,4′,5′-trichlorophenyl)propanoate 5 and the appropriate aryl or alkyl isothiocyanate. 2,4,5-Trichloroacetophenone 4, required for the synthesis of 5, is successfully prepared by Friedel-Craft's acetylation of 1,2,4-trichlorobenzene in 82% yield. The structures of the new compounds 5 and 6a-h are based on microanalytical and spectral (NMR, MS(EI), and HRMS) data.
