130649-72-8

Upstream product

• 59662-65-6 methylthiomethyl p-tolyl sulfone 
• 130649-72-8 1-(methylthio)-1-(p-tolylsulfonyl)-1,3-pentadiene 
• 123-73-9 trans-Crotonaldehyde 
• 162777-19-7 <(4-methylphenyl)sulfonyl>(trimethylsilyl)methyl methyl sulfide 

Downstream Products

• 130649-79-5 1-Methyl-4-((E)-2-methylsulfanyl-1-phenyl-hexa-3,5-diene-2-sulfonyl)-benzene 
• 139261-78-2 (4E)-6-phenyl-2,4-hexadienal 
• 121742-60-7 (4Z)-6-phenyl-2,4-hexadienal 
• 139452-86-1 1-Methyl-4-[9-((1E,3E)-4-methylsulfanyl-buta-1,3-dienyl)-heptadecane-9-sulfonyl]-benzene 
• 139452-80-5 1-((3E,5E)-2-Benzyl-6-methylsulfanyl-1-phenyl-hexa-3,5-diene-2-sulfonyl)-4-methyl-benzene 
• 132760-63-5 1-(methylthio)-5-(p-tolylsulfonyl)-1,3-tetradecadiene 
• 139452-81-6 1-((1E,3E)-5-Butyl-1-methylsulfanyl-nona-1,3-diene-5-sulfonyl)-4-methyl-benzene 
• 139452-84-9 1-Methyl-4-((3E,5E)-2-methyl-6-methylsulfanyl-1-phenyl-hexa-3,5-diene-2-sulfonyl)-benzene 
• 132760-62-4 1-(methylthio)-6-phenyl-5-(p-tolylsulfonyl)-1,3-hexadiene 
• 139452-82-7 1-Methyl-4-[1-((1E,3E)-4-methylsulfanyl-buta-1,3-dienyl)-cyclohexanesulfonyl]-benzene 
• 132760-74-8 (E)-6-Phenyl-5-(toluene-4-sulfonyl)-hex-2-enal 
• 132760-60-2 5-(methylthio)-5-(p-tolylsulfonyl)-1,3-pentadiene 
• 132760-61-3 1-(methylthio)-5-(p-tolylsulfonyl)-1,3-pentadiene 
• 132760-65-7 4-benzyl-5-phenyl-2,4-hexadienal 

Relevant academic research and scientific papers

A novel 1,5-rearrangement of a sulfonyl group in a 1-sulfenylated 2,4-alkadiene

1-Substituted 1-methylthio-2,4-pentadien-1-yl sulfones (4) smoothly underwent a 1,5-rearrangement of a sulfonyl group by the action of silica gel. Its application to a new synthesis of conjugated dienones is also described.

A New and Convenient Preparation of Conjugated Dienals

For preparation of 5-monosubstituted or 5,5-disubstituted 2,4-dienals, 1-(methylthio)-5-(p-tolylsulfonyl)-1,3-pentadiene (4) is revealed to be an important precursor.When 5-(methylthio)-5-(p-tolylsulfonyl)-1,3-pentadiene, that is easily obtainable from (methylthio)methyl p-tolyl sulfone, was treated with silica gel, 1,5-rearrangement of p-tolylsulfonyl group occurred to give 4.The conditions for mono- or dialkylation of 4 followed by hydrolysis leading to the dienals are desribed.